The Para-Bombay Phenotype (Hz) in a Thai Family
Keywords:
para-Bombay, Bombay phenotype, Hz phenotype, H-deficiency, Thai familyAbstract
Abstract : The Bombay phenotype, one of very rare blood type is found and reported among Thai population. Up all now, only one classical Bombay blood type has been reported in a Southem Thai-Musim pattent and 10-15 para-Bombay phenotypes have been reported by the National Blood Centre. Thai Red Cross Society. This is a report of a case of the para-Bombay phenotype (Hz type) found in the Northern Thai family.
The ABH, D and Lewis blood group antigens on red cell were examined in 14 members of the family individuals. Saliva ABH substances were also determined by hemagglutination inbibition technique. Investigation results revealed that three members of the family (the propositus, his brother and sister) inhented the hh genes from their parents and appeared to be Ohm (OHm : Hz-
Type), sectetor status (SeSe/Sese) and Le (a-b+). The other counsin was corresponded to Ahm (OAHm). The high level of anti-H was also present in the plasma of the propositus. Crossmatching result showed compatibility with all OHm and Oh phenotypes but elastrated strongly incompatibility with ordinary group O, OAHm and OBHm phenotypes.
Further testings of 104 blood donors living in the same distict as the propositus were made, but no H-deficient blood was found. Later on, two more cases of deficient blood were accidentally found in different unrelated patients.
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