A 31-year-old Woman with Acute Myeloid Leukemia and Chronic Recurrent Monoarticular Arthritis
Keywords:
Acute myeloid leukemia, Fungal arthritis, Chronic recurrent arthritisAbstract
Abstract: A 31-year-old woman was diagnosed acute myeloid leukemia (AMI). After receiving induction chemotherapy, she developed acute monoarticular arthritis at nght knee. Joint fuid examination did not show microorganism. She had 4 more recurrent attacks of arthritis at the same joint after consolidation chemotherapy. At the last examination of joint fuid it showed budding veast.
The patient was treated with amphotericin B 1 mg/kg/d and joint symptom was completely resosolved.Fungal arthritis should be suspected in patients with chronic recurrent moncarticular arthritis especially after receiving high dose chemotherapy, having prolonged bone marrow hypoplasia and febrle neutropenia. Amphotericin B is the drug of choice and should be initiated promptly after the definite diagnosis.
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