A Case of Rh (D) Hemolytic Disease of the Newborn at Police General Hospital
Keywords:
Rh-HDN, Anti-DAbstract
Abstract: A report case of Rh (D) hemolytic disease of the newbom. A female infant, and her mother had been referred to Police General Hospital, where the infant had been noticed to have jaundice at the age of 2 days. Blood typing of the baby revealed "O", Rh positive and posive direct antiglobuin test. The matemal blood was investigated for blood typing and antibody screening, of which the results were 'B", Rh negative with anti-D antibody of a titer 1:128. The had been reported to have a severe hyperbilirubinemia with the highest serum bilirubin to a level of 26.8 mg/dL. The baby had two occasions of blood exchange, along with phototherapy for 6 days, and discharged from hospital with uneventhul condions. This case is a good example for reminding medical staffs to concern the postpartum Rh (D) isoimmunization prophylaxis.
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Blanchette V, Doyle J, Schmidt B, Zipursky A. A. Hematology. In: Averey GB, Fletcher MA, MacDonal MG, eds. Neonatology Pathophysiology and Management of the Newborn. 4th ed. Philadelphia: JB Lippincott Co, 1994;962-6.
Mollison PL, Engelfriet CP, Contreras M. Blood transfusion in clinical medicine. 8th ed. Oxford: Blackwell Scientific Publication, 1987.
Huchcroft S, Gunton P, Bowen T. Compliance with postpartum Rh isoimmunization prophylaxis in Alberta. Can Med Assoc J 1985;133:871-5.
Vomund SL, Witter SF. Advanced techniques for the treatment of severe isoimmunization. Am J Matern Child Nurs 1994;19:18-23.
Bowman JM, Controversies in Rh prophylaxis. Am J Obstet Gynecol 1985;151:289-94.
Tannirandorn Y, Rodeck CH. New approaches in the treatment of hemolytic disease of the fetus. Baillieres Clin Haematol 1990;3:289-320.
Bowman JM. Suppression of Rh immunization. A review Obstetrics and Gynecology 1978,52:385-93.
Baskett TF, Parsons ML. Prevention of Rh(D) alloimmunization: a cost-benefit analysis. Can Med Assoc J 1990;142:337-9.
Clarke CA. Preventing rhesus babies : the Liverpool research and follow up. Arch Dis Child 1989;64:1734-40.
สถิติหน่วยทารกแรกเกิด โรงพยาบาลจุฬงกรณ์ พ.ศ.ศ. 2529-2538 และปี พ.ศ. 2540-2541.
Hsia Dyy, Allen FH Jr, Gellis SS, Diamond LK. Erythroblastosis. VIII. Studies of serum bilirubin in relation to kernicterus. N Engl J Med 1952;247:668-71.
Zavala C, Salamanca F. Mothers at risk of alloimmunization to the Rh(D) antigen and availability of gammaglobulin at the Maxican Institute of Social Security. Arch Med Res 1996 Autumn;27:373-3-6.
Hughes RG, Craig JI, Murphy WG, Greer IA. Causes and clinical consequence of Rhesus (D) haemolytic disease of the newborn: a study of a Scottish population, 1985-1990. Br J Obstet Gynecol 1994;101:297-300.
จริยา สายพิณ และคณะ: การป้องกันโรคเม็ดเลือดแดงแตก. ใน: เด็กเกิดใหม่ที่เกิดจากแม่ Rก negative. วารโลหิตวิทยาและเวชศาสตร์บริการโลหิต 1998;8:123-7.
Maayan-Metzger A, Schwartz T, Sulkes J, Merlob P. Maternal anti-D prophylaxis during pregnancy dose not cause neonatal haemolysis. Arch Dis Child Hetal Neonatal Ed 2001;84:60-2.
Urbaniak SJ, Greiss MA. Rh D haemolytic disease of the fetus and the newborn. Blood Rev 2000;14:44-61.
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