Massive pleural effusion as a presentation of extramedullary hematopoiesis among patients with non transfusion dependent beta-thalassemia

Authors

  • Khetwasan Arunphong Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Pajaree Chairat Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Nonthakorn Hantrakun Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Thanawat Rattanathammethee Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Chatree Chai-Adisaksopha Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Lalita Norasetthada Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Adisak Tantiworawit Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Sasinee Hantrakool Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Pokpong Piriyakhuntorn Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • Teerachat Punnachet Division of Hematology, Faculty of Medicine, Chiang-Mai University
  • EKARAT RATTARITTAMRONG Division of Hematology, Faculty of Medicine, Chiang-Mai University

Keywords:

Thalassemia, Extramedullary hematopoiesis, Pleural effusion

Abstract

Thalassemia is one of the most common hemoglobinopathies. Beta-thalassemia results from a decreased or absent production of the beta-globin chain of hemoglobin. Extramedullary hematopoiesis (EMH) is one of the complications of beta-thalassemia, primarily seen among non transfusion dependent patients. EMH predominately occurs in the spleen, liver and lymph nodes but has been reported in almost all organs. Despite this, EMH is rare regarding presented with serous effusions. We present a case report of EMH occurring in the pleura with pleural effusion in a patient with beta thalassemia together with discussion of the diagnostic approaches and treatment implications.

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References

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Published

2024-06-23

Issue

Vol. 34 No. 2: April-June 2024

Section

รายงานผู้ป่วย (Case report)

License

Copyright (c) 2024 Journal of Hematology and Transfusion Medicine

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