Postpartum Splenic Artery Thrombosis Followed by Splenic Rupture in Patient with Hemoglobin H Disease: A Case Report and Review Literatures
Keywords:
Artery thrombosis, Hemoglobin H Disease, Splenic ruptureAbstract
Abstract: A 26-year-old Thai female who had underlying Hemoglobin H disease came with acute abdominal pain without any history of trauma. She was 38 weeks gestation and just 15 hours post delivery. On physical examination, she was mild pallor with moderate tenderness at left upper quadrant. The CT scan of abdomen showed splenic aterial thrombosis. The other investigations to demonstrate hypercoagulable stage including antithrombin IIl, protein C, protein S, factor V leiden mutation, homocysteine, and Jupus anticoagulant were normal. She was successful treated with low molecular weight heparin and followed by warfarin.
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References
Letsky E, SwietM. Matemal hemostasis: Coagulation problem of pregnancy. In: Loscalzo J, Schafer A eds. Thrombossis and hemorhage. Boston: Blackwell Scientific 1994:965-98.
Greengard JS, Sun X, Xu X, Fernandez JA, Griffin JH, Evatt BL. Activated protein C resistance cause by Arg 506GIn mutation infactor Va. Lancet 1994;343:1361.
Poort SR, Rosendaak FR, Reitsma PH, Bertina RM.A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3398-703.
Naikai K, Itoh C, Miura Y, Hotta K, Musha T, Iroh T, et al. Deletion polymorphism of the angiotensin I converting enzyme is associated with serum ACE concentration and increased risk for CAD in the Japanese. Circulation 1994;90:2199-202.
Grandone E, Margaglione M, Colaizzo D, D'Andrea G, Cappucci G, Brancaccio V, et al. Gene susceptibility to pregnancy-related venous thromboembolism: Roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations. Am J Obstet Gynecol 1998;179:1324-28.
Borgna Pignatti C, Carnelli V, Caruso V, et al. Thromboembolic events in beta thalassemia major: an Italian multicenter study. Acta Haematol 1998;99:76.
Tso SC, Chan TK, Todd D. Venous thrombosis in hemoglobin H disease after splenectomy. Aust N Z J Med 1982;12:635-8.
Michaeli J, Mittelman M, Grisaru D, Rachmilewitz EA. Thromboembolic complications in beta thalassemia major. Acta Haematol 1992;87:71-4.
Borgna Pignatti C, Carnelli V, Caruso V, et al. Thromboembolic event in beta thalassemia major: an Itarian multicenter study. Acta Haematol 1998;21:812-6.
Winichagoon P, Fucharoen S, Wasi P. Increased circulating platelet aggregates in thalassemia. Southeast Asian J Trop Med Public Health 1981;12:556-60.
Del Principe D, Menichelli A, Di Giulio S, De Matteis W, Cianciulli P, Papa G. PADGEM/GMP-140 expression on platelet membranes from homozygous beta thalassemic patients. Br J Haematol 1993;84:111-7.
Bunyaratvej A. Differentiation of platelets from red cell fragments using laser technology: comparison between splenectomized and nonsplenectomized thalassemic patients. Southeast Asian J Trop Med Public Health 1993;24:250-2.
Bunyaratvej A, Komanasin N, Sriurairatana S, Fucharoen S. Morphological assessment of platelet activation in thalassemia. Southeast Asian J Trop Med Public Health 1992;23:60-4.
Butthep P, Bunyaratve] A, Funahara Y, et al. Alterations in vascular endothelial cell-related plasma proteins in thalassemic patients and their correlation with clinical symptoms. Thromb Haemost 1995;74:1045-59.
Manodori AB, Barabino GA, Lubin BH, Kuypers FA. Adherence of phosphatidylserine-exposing erythrocytes to endothelial matrix thrombospondin. Blood 2000;95:1293-300.
Wiener E, Wanachiwanawin W, Chinprasertsuk S, et al. Increased serum levels of macrophage colonystimulating factor (M-CSF) in alpha- and beta-thalassemia syndromes: correlation with anaemia and monocyte activation. Eur J Haematol 1996;57:364-9.
Visudhiphan S, Ketsa-Ard K, Tumliang S, Piankijagum A. Significance of blood coagulation and platelet profiles in relation to pulmonary thrombosis in beta-thalassemia/Hb E.Southeast Asian J Trop Med Public Health 1994;25:449-56.
Shirahata A, Funahara Y, Opartkiattikul N, Fucharoen S, Laosombat V, Yamada K. Protein C' and protein S deficiency in thalassemic patients. Southeast Asian J Trop Med Public Health 1992;23:65-73.
Helley D, Eldor A, Girot R, Ducrocq R, Guillin MC, Bezeaud A. Comparison of the procoagulant activity of red blood cells from patients with homozygous sickle cell disease and 3-thalassemia. Thromb Haemost 1996;76:322-7.
Kuypers FA, Lewis RA, Hua M, et al. Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V. Blood 1996;87:1179-84.
Eldor A, Durst R, HY-AM E, et al. A chronic hypercoagulable stage in patient with beta-thalassemia major is aleeady present in childhood. Br J Haematol 1999;107,739-46.
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