Multiple myeloma presented with tumor fever

Authors

  • Pisa Phiphitaporn Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Thailand
  • Piti Ungarreevittaya Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Thailand
  • Theerin Lanamtieng Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Thailand
  • Chinadol Wanitpongpun Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Thailand
  • Nattiya Teawtrakul Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Thailand

Keywords:

multiple myeloma, prolong fever, tumor fever

Abstract

Multiple myeloma is a malignant neoplasm of plasma cells that causing prolonged fever due to infectious cause. This is because myeloma cells can suppress normal immunoglobulin production. Rarely, prolonged fever can be caused by the tumor itself. In our multiple myeloma case, the patient presented with prolonged fever despite extensive investigation and negative test results for infection. Fever persisted during antimicrobial treatment and subsided after myeloma treatment. Laboratory tests revealed monoclonal gammopathy and monoclonal plasma cells. After treating with bortezomib, cyclophosphamide and dexamethasone (VCD) regimen, followed by autologous stem cell transplantation, the patient’s disease status was in stringent complete remission.

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ISSN XXXX-XXXX (Print) ISSN XXXX-XXXX (Online)

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Published

2023-09-26

Issue

Vol. 33 No. 3: July-September 2023

Section

รายงานผู้ป่วย (Case report)

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Copyright (c) 2023 Journal of Hematology and Transfusion Medicine

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