Protein-losing enteropathy as a rare manifestation of neuroblastoma: a case report
Keywords:
neuroblastoma, protein-losing enteropathy, intestinal lymphangiectasia, childrenAbstract
Abstract:
An 11-month-old girl presented with generalized edema, fever and secretory diarrhea. Investigations
revealed fat malabsorption and hypoalbuminemia; protein-losing enteropathy was confirmed with a Tc-99m
albumin scan, and subsequent endoscopy with biopsy was performed, which revealed intestinal lymphangiectasia without evidence of malignancy. She was initially treated for primary intestinal lymphangiectasia with intravenous albumin and fat-free enteral feeding without improvement. After two months of hospitalization, a scalp nodule was noticed, and the biopsy result was consistent with neuroblastoma. Staging was completed, revealing the primary tumor had originated from the left adrenal gland with multiple extensive local and distant metastases. She received induction chemotherapy and partial tumor removal followed by one cycle of consolidative chemotherapy. Unfortunately, she was lost to follow-up and died approximately one year after diagnosis
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References
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