Resilience as a mediator between positive psychosocial factors, psychological well-being, and depression among patients with major depressive disorder

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Nanchatsan Sakunpong
Kwanjai Ritkumrop


Background: Major Depressive Disorder (MDD) is a mental health problem that affects people’s lives. Although there are treatments that employ drugs and psychotherapy to decrease depression, there are a lack of studies on positive psychosocial factors, especially resilience, promotion of well-being and coping with depression.

Objective: This study aimed to investigate the positive psychosocial factors on psychological well-being and depression mediated by resilience.

Methods: A cross-sectional study was employed with a sample consisting of 250 MDD patients who had been diagnosed by a psychiatrist and met the Diagnostic and Statistical Manual of Mental Disorders criteria. Data analysis was conducted with path analysis.

Results: The results found that gratitude, mindfulness and perceived social support can predict resilience and resilience can predict psychological well-being as well as depression. Also, gratitude can predict depression.

Conclusions: Resilience is an important mediator between gratitude, mindfulness, perceived social support and psychological well-being as well as depression among MDD patients. Therefore, the results from this study can be used to provide care to MDD patients based on the concept of positive psychology, which emphasizes the growth and flourishment of human potential development.


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Sakunpong, N., & Ritkumrop, K. (2021). Resilience as a mediator between positive psychosocial factors, psychological well-being, and depression among patients with major depressive disorder. JOURNAL OF HEALTH SCIENCE RESEARCH, 15(2), 138-149. Retrieved from
นิพนธ์ต้นฉบับ (Original Articles)


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