Factors predicting the occurrence of stroke in hypertensive patients in Khon Kaen province

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Anekpong Hoikum
Luckawee Piyabanditkul
Wirin Kittipichai


Background: Factors predicting the occurrence of stroke in hypertensive patients can provide a guideline for risk behavior modification support in order to prevent or delay stroke.Objectives: The purpose of this research was to study predictive factors of stroke in hypertensive patients in Khon Kaen province.Methods: This case-control study of patients with hypertension who were treated at healthcare units in Khon Kaen province. The sample of 348 patients who had had a stroke less than 1 year was defined as a case group, and 696 patients without stroke defined as a control group. Data collection was performed by interview and a review of patients’ medical records. Data were analyzed by utilizing descriptive statistics, chi-square, and logistic regression analysis.Results: The results of logistic regression analysis showed that the factors that significantly predicted the stroke occurrence in hypertensive patients included having had hypertension for at least 5 years (ORadj 10.66, 95%CI 6.38-17.81), systolic blood pressure >140 mmHg (ORadj 6.55, 95%CI 3.94-10.88), and diastolic blood pressure > 90 mmHg (ORadj 4.40, 95%CI 3.11-6.22), male gender (ORadj 2.66, 95%CI 1.91-3.71), and family history with stroke (ORadj 2.36, 95%CI 1.51-3.70).

Conclusions: Based on the findings, these factors should be taken into account for the prevention of the occurrence of stroke in hypertensive patients. Healthcare providers should emphasize health promotion activities and behavior modifications for these patients to reduce risk factors and delay stroke occurrence.



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Hoikum, A., Piyabanditkul, L. ., & Kittipichai, W. . (2020). Factors predicting the occurrence of stroke in hypertensive patients in Khon Kaen province. JOURNAL OF HEALTH SCIENCE RESEARCH, 14(2), 82–92. Retrieved from https://he01.tci-thaijo.org/index.php/JHR/article/view/240570
นิพนธ์ต้นฉบับ (Original Articles)


World Stroke Organization. World Stroke Organization: Annual report. [Internet]. 2016 [cited 2017 Oct 1]; Available from: https://www.world-stroke.org/about-wso/wso-annual-report.

Strategy and Planning Division. Public Health Statistics A.D. 2016. Nonthaburi: Strategy and Planning Division, Ministry of Public Health; 2017. (in Thai).

Division of Non Communicable Diseases. Annual Report 2016. Nonthaburi: Ministry of Public Health; 2016. (in Thai).

Health Data Center, Ministry of Public Health. [internet]. 2017 [cited 2017 Aug 15]; Available from https://kkhdc.moph.go.Th/ hdc/reports/page.php?cat_id=6a1fdf282fd 28180eed7d1cfe0155e11.

Thai Hypertension Society. 2019 Thai guidelines on the treatment of hypertension. Chiang mai: Trick Think; 2019. (in Thai).

Meinert CL, Tonascia S. Clinical Trails Design Conduct and Analysis. New York: Oxford University Press; 1996.

Sagare S, Rajaderkar S, Girigosavi, S. Certain modifiable risk factors in essential hypertension: a case-control study. National J Community Med. 2011;2(1):9-13.

Keiko M, Kei A, Michihiro S, Ryusuke I, Megumi T, Miki H, et. al. Risk Factors for Stroke among Young-Old and Old-Old Community-Dwelling Adult in Japan: The Ohasama Study. J Atheroscler Thromb. 2017;24(3):290-300.

Wang J, Wen X, Li w, Li X, Wang Y, Lu w. Risk Factors for Stroke in the Chinese Population: A Systematic Review and Meta-Analysis. J stroke Cerebrovasc Dis. 2016;3:509-17.

Puthawong W, Kittipichai W, Silawan T, Monsawaengsup C. Cerebrovascular Disease Risk Factors Among Hypertensive Patients in Phayao Province. Journal of Public Health. 2014;44(1):30-45. (in Thai).

Parjaree K. Rehabilitation for stroke patients: basic knowledge in stroke. Bangkok: Medical education technology center Mahidol University; 2004. (in Thai).

Majavong M. Stroke in the elderly. Journal of Thai Stroke Society. 2019;18(1):59-74. (in Thai).

Martin J, Xavier D, Chin L, Hongye Z, Siu LC, Purnima R, et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. [internet]. 2010 [cited 2017 Aug 10]; Available from https://www.thelancet.com.

Suchat H, Niphon P, Nijasri C, Somchai T, Jithanorm S. Prevalence of Stroke and Stroke Risk Factors in Thailand: Thai Epidemiologic Stroke (TES) Study. Journal of Medical Association of Thailand. 2011;94(4):427-36. (in Thai).