Self-management support for slow progression in patients with pre-dialysis chronic kidney disease: a systematic review and meta-analysis

Main Article Content

Tadsaneewan Gantagad
Porntip Sareeso


Background: Studies of the self-management support have emerged widely in chronic diseases, including chronic kidney disease. These mainly include European and American studies. Only a small number of studies  have been conducted in the context of Asian countries, including Thailand.

Objectives: The aim of this study was to conduct a systematic literature review and conduct the meta-analysis to confirm the eGFR decline of self- management support program in patients with pre-dialysis in Thailand.

Method: The search was limited to research related to self-management support in patients with chronic kidney disease written in English or Thai and published from 2013 – 2017, from both International and Thai databases. After applying the eligibility criteria, 3 from 9 studies were included for data extraction and was subjected to a systematic review and meta-analysis.

Results: Analysis of three research studies in level 2 based on The Joanna Briggs Institute criterion levels of evidence showed a statistically non-significant difference of efficacy in self-management support program. The mean difference = –0.599 mL/min/1.73m2; 95% CI [ -5.66, 4.47]; p = 0.82.

Conclusion: Policy makers of health care organizations should develop a policy on promoting self-management support for the delay of kidney disease progression in patients with pre-dialysis chronic kidney disease. This should also include a process of how stakeholders can be involved with the care to slow down the deteriorate process which will respond to health care needs according to varies contexts.


Download data is not yet available.

Article Details

How to Cite
Gantagad, T., & Sareeso, P. (2020). Self-management support for slow progression in patients with pre-dialysis chronic kidney disease: a systematic review and meta-analysis. JOURNAL OF HEALTH SCIENCE RESEARCH, 14(3), 157–168. Retrieved from
นิพนธ์ต้นฉบับ (Original Articles)


Nathan RH, Samuel TF, Jason LO, Jennifer AH, Christopher AO, Daniel SL, et al. Global prevalence of chronic kidney disease – a systematic review and meta-analysis. PLoS One. 2016;11(7):e0158765.

Lee S, Chung, C. Health behaviors and risk factors associated with chronic kidney disease in Korean patients with diabetes: the Fourth Korean National Health and Nutritional Examination Survey. Asian Nurs Res (Korean Soc Nurs Sci). 2014;8(1):8-14.

Yeary KH, Aitaoto N, Sparks K, Ritok-Lakien M, Hudson JS, Goulden P, et al. Cultural adaptation of diabetes self-management education for Marshallese Residing in the United States: lessons learned in curriculum development. Prog Community Health Partnersh. 2017;11(3): 253-61.

Kummatic A, Markrat M. Using the systematic review to provide a complete summary on a research question in evidence-based practice: a 3-step method. The Southern College Network Journal of Nursing and Public Health. 2016;3(3): 246-59. (in Thai).

Chanprakhon C. Effects of empowerment based self-management support program on self-management behaviors and clinical indicators among patients with diabetic nephropathy. [Independent study]. Khon Kaen: Khon Kaen University; 2013. (in Thai).

Srisuwannaphop P. Effectiveness of chronic kidney disease patient care in diabetes mellitus clinic at Chattrakan hospital. [Thesis]. Bangkok: Silpakorn Universitiy; 2012. (in Thai).

Thungtong S. Effects of self-management support program for delayed progression of diabetic nephropathy on self-management behaviors and clinical outcomes in patients with uncontrolled type 2 diabetes mellitus. [Thesis]. Songkla: Prince of Songkla University; 2013. (in Thai).

Nicole E, Jonathan C, Adrian B, Karine M, Valeria S, Allison T. Lifestyle behavior change for preventing the progression of chronic kidney disease: a systematic review. BMJ Open. 2019;9(10):e031625.