Using triglyceride-glucose index to predict diabetes in prediabetic individuals
Keywords:
Triglyceride-glucose index, Prediabetes, Diabetes, PredictAbstract
Type 2 diabetes is on the rise today, with the main risk group for developing diabetes being people with prediabetes. According to studies on diabetes prediction, higher triglycerides-glucose index values were associated with higher incidence of diabetes. However, there are limited studies of diabetes prediction with triglycerides-glucose index in prediabetes individuals. This study aims to study the ability to predict the occurrence of diabetes in people with prediabetes using the triglycerides-glucose index. The historical cohort study was conducted in Bhumibol Adulyadej Hospital personnel from 1 January 2017 to 31 December 2022 and tracked the incidence of diabetes by dividing the initial triglycerides-glucose index into groups greater than or equal to 9.02 and lower than 9.02. The results showed that the group with a triglyceride-glucose index greater than or equal to 9.02 had a 2.5-fold risk (p = 0.028) compared to the group with a triglyceride-glucose index less than 9.02. The cut-off point is 8.64 (sensitivity 75% specificity 50%) When comparing the ability to predict diabetes with glucose with the ROC curve, the triglycerides-glucose index and glucose AUC were 0.69 and 0.79, respectively. In conclusion, triglyceride-glucose index can predict diabetes in prediabetes population but when compared to the glucose. Triglycerides-glucose index has an inferior ability to predict diabetes.
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