Comparative Effectiveness of Dual Therapy with Aspirin and Clopidogrel versus Aspirin Monotherapy for the Treatment of Ischemic Stroke at Takfa Hospital, Nakhon Sawan Province
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Abstract
The purpose of this research was to study the effectiveness of treating ischemic stroke with aspirin combined with clopidogrel, comparing the effectiveness with using aspirin alone. This is a retrospective study, that analyzes causes to outcomes. Studied the incidence rate of stroke, Death due to stroke, Deaths from cerebrovascular causes including cardiovascular disease, and the occurrence of bleeding that requires hospital treatment through fluid administration or blood transfusion within 1 year after receiving treatment in stroke patients treated at Takfa Hospital during the period from 1 January 2018 to 1 January 2022. This research study used a case record form that the researcher created for use in data collection and research studies and passed the test. The accuracy of the content questionnaire (Content Validity) by experts. The data was analyzed using descriptive statistics and inferential statistics, analyzing multiple variables with multiple log-binomial regression analyses or multiple Poisson regression analyses, reported with Risk Ratio (RR) values as appropriate to the data. The results showed that treatment of ischemic stroke with aspirin plus clopidogrel. There was no statistical difference between treatment with aspirin alone.
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