The associations of alike drugs, adjacent drugs, poly-drug prescriptions, and period of pharmacy services to the risk of medication errors in pharmacy dispensing: Case study in pharmacy department, Sai Mun hospital
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Abstract
The purpose of this cross-sectional study was to assess the associations of alike drugs, drug placement,
poly-pharmacy prescriptions, and period of pharmacy services to the risk of pre-dispensing and dispensing
error: a case study at pharmacy department, Sai Mun hospital. The prescriptions from out-patient department were collected for 4 months from August 1st, 2009 to November 30th, 2009 (Monday to Friday from 8.00-12.00 am and 13.00-16.00 pm). Medication errors and the data of alike drugs, drug placement,
poly-pharmacy prescriptions, and period of pharmacy services were recorded in medication errors and
associated factors forms. Medication error was analyzed by descriptive statistics and the associations were
explained by binary multiple logistic regression analysis. Occurred of 8,053 sampled prescriptions, 203
medication erorrs (2.5%) occured in pharmacy department, of which 197 errors (2.45%) were pre-dispensing
errors and 6 erorrs (0.07%) were dispensing errors. The binary multiple logistic regression analysis showed
the significant factors related to medication errors as follow (p < 0.05), the prescriptions with sound-alike drugs were more likely to have medication errors in pharmacy dispensing for 1.706 times over those withoutsound-alike drugs (OR = 1.706, 95%CI = 1.102-2.643), the prescriptions with various strengths of the same drug were more likely to have medication errors for 2.074 times than those witnout with those without various strength of same drug (OR = 2.074, 95%CI = 1.204-3.575), the medication error was more likely to occur with the prescription with 7-11, and > 11 drug items than those with single item for 9.490, and 18.907 times, respectively (OR = 9.490, 95%CI = 2.098 -42.926 for 7-11 drug items, and OR = 18.907, 95%CI =
3.385 -105.587 for > 11 drug items), and morning pharmacy services were more likely to have medication
errors for 1.973 times comparing with afternoon service (OR = 1.973, 95%CI = 1.221 - 3.187).
The associations between medication errors and these following variables; sound-alike drugs, various
strengths of same drug, poly-pharmacy prescriptions, and performing pharmacy services in the morning could help pharmacists and assistants for increase awareness to prevent and decrease medication errors in pharmacy dispensing, Sai Mun hospital.
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References
Adnan B, Bryony DF. and Nick B. The frequency andpotential causes of dispensing error in ahospital pharmacy. Pharm World Sci 2005;27: 182- 90.
Brennan TA, Leape LL, Laird NM, et al. Incidence ofadverse events and negligence in hospitalizedpatients. Results of the Harvard MedicalPractice Study I. N Eng J Med 1991; 324:370-76.
Institute of Medicine (IOM). Preventing MedicationErrors. 2008 [cited 2008 July 14]. Availablefrom: http://www.iom.edu/Object.File/Master/35/943/medication%20errors%20new.pdf.
Kohn LT, Corrigan JM, and Donaldson MS. (Eds.)2000. To Err Is Human: Building a Safer HealthSystem. Washington D.C: National AcademyPress; 2000.
Nichols P, Copeland TS, Craib LA, et al. Learningfrom error: identifying contributory cause ofmedication errors in an Australian hospital. MJA2008; 188(5): 276-79.
Tuula T, Virpi G. and Marja A. A system approach todispensing errors: a national study onperception of the finish community pharmacist.Pharm World Sci 2008; 30: 823-33.