Adherence to Evidence Based Guideline in Treatment of Hypertension

Main Article Content

Pornsiri Jaroonsawanya
Phayom Sookaneknun
Chalongchi Toondee
Narumol Koonjarenrat
Kanjanaporn Taratai

Abstract

Evidence Based Guideline in Treatment of Hypertension improves cardiovascular outcomes. The
objective of this study was to assess the adherence to the treatment of hypertension following the Joint
National Commission on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC)
guidelines in 2001 (JNC VI) and 2005 (JNC VII). This study was a retrospective cross-sectional study
in hypertensive patients who received medications or registered for the treatment (ICD 10) beginning in
January 2001 following through December 2005. Medication review, blood pressure, laboratory test,
hospital admission, death were assessed. There were 1,015 patients, and sampling for 168 patientsû
profile which 102 patientsû profile were completed for analysis. The average age was 61.1±11.8 years.
Most of them were female (70.6%) and had only hypertension (49.0 percent). Most of the patients
received monotherapy (49.0%). The frequently prescribed medications were diuretics (39.2%),
angiotensin-converting enzyme inhibitors (35.3%). During 5 years of study, there were 5 patients died
and 4 of them died from cardiovascular disease. Average hospital admission rate was 1.86 times per
patient in 2003. No difference significance in blood pressure at the time comparing between in 2001 and
2005. Overall percentage of adherence to treatment according to JNC VI was 56.7% in 2001 and
according to JNC VII guideline was 46.43% in 2005 Prospective study may show more clinical practice
changes adhering to the guidelines.

Article Details

Section
Pharmaceutical Practice

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