Treatment Outcome and Cost of Rationale Antibiotic Use Implementation In Mahasarakham University Pharmacy
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Abstract
Introduction Unnecessary use of antibiotics is cause of antimicrobial resistance. Recently, Antibiotics Smart Use (ASU) was a model to promote the rational use of medicines and counteract antimicrobial resistance. Objective The objectives of this study were to assess the treatment outcome and cost of Antibiotics Smart Use (ASU) guideline for patients with pharyngitis and diarrhea in 3 branches of university pharmacy. Materials and Methods The study design of this study was descriptive. The sample consisted of patients with pharyngitis and diarrhea who attended the service at the university pharmacy during October to December 2012. Patient with pharyngitis were assessed and classified by the McIsacc score. Diarrheal patients were divided into no receiving and receiving antibiotics group. All patients were followed up at 5 days after treatment for pharyngitis and 3 days after treatment for diarrhea. Results Most of pharyngitis patients were classified as 0-1 score (53.8%). Patients who were classified as 2-3 scores who received, did not received antibiotics and ≥4 scores were 10.2%, 29.1% and 2.4%,respectively. Most of diarrheal patients did not receive antibiotics (85.7%). After followed up, patients with pharyngitis had recovered (71.7%); 0-1 score (75.7%), 2-3 scores who received antibiotics (69.2%), 2-3 scores who did not received antibiotics (64.9%) and ≥4 scores(66.7%). The most of diarrheal patients had recovered (95.2%). For pharyngitis, patients with 2-3 scores who received antibiotic and did not receive antibiotic had the highest and lowest of average cost per person, respectively. The patients with 2-3 scores who received antibiotic had the cost per person more than patients with ≥4 scores. The diarrheal patients who received antibiotics had the cost per person more than another group. Overall, satisfaction level of patients was high to very high. Conclusion The results of this study were consistent with antibiotics rational principles of ASU project in hospital. Therefore, the application of this principle in community pharmacies will contribute patients to receive antibiotics appropriately.
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