Antioxidant and Antimutagenic Activities of Phellinus rimosus
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Abstract
Introduction: Phellinus rimosus is fungi in the family Hymenochaetaceae. It commonly grows in northeast of Thailand. In traditional medicine, P. rimosus was used as an ingredient in cancer treatment drug, herpes, earache and rash. Objective: This study investigated the antioxidant and antimutagenic activities of ethanol, water and procedure from alkaloid extraction of P. rimosus. Methods: Antioxidant activity was studied using Scavenging activity on 2,2 - Diphenyl- picrylhydrazyl radical assay (DPPH assay) and Ferric reducing antioxidant power assay (FRAP assay). Antimutagenic activity was studied by Ames mutagenecity assay with Salmonella typhimurium strain TA98 and TA100 against mutagen, 1-aminopyrene treated with nitrite. Results and conclusion: The ethanol extract of P. rimosus was the best antioxidation and antimutagenic activities in this model. Thus, P. rimosus is an interesting to developed for natural product in the future study.
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References
Ajith TA, Janardhanan KK. “Antimutagenic effect of Phellinus rimosus (Berk) Pilat against chemical induced mutations of histidine depentdent Salmonella typhimurium strains”. Food Chem Toxicol 2011; (49): 2676-2678.
Benzie I.F.F., Strains J.J., “Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration”. Methods Enzymol 1999; [299]: pp15-27.
Calomme M., Pieters L., Vlietinck A., Berghe CV., “Inhibition of bacterial mutagenesis by Citrus flavonoids”. Planta Med 1996; [62]: pp22-26.
Chaimutti P. Antioxidant of Plants. Songklanakarin university 2547.
Chu YH, Chang CL, Hsu HF. “Flavonoid content of several vegetables and their antioxidant activity”. Sci Food Agric 2000; 80(5): 561-566.
Kangsadalampai K., Butryee C., Manoonphol K., “Direct mutagenicity of the polycyclic aromatic hydrocarbon-containing fraction of smoked and charcoal-broiled foods treated with nitrite in acid solution”. Food Chem Toxicol 1996;(35): 213-218.
Maron DM.and Ames B.N., “Revised methods for Salmonella mutagenicity test”. Mutant Res1983; [444]: pp451-461.
Song YS, Kim SH, Sa JH, Jin C, et al. “Anti-angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus”. J Ethnopharmacol 2003;(88).
The Medical Foundation Thailand, Bureau of Sanatorium and Art of Healing. “Thailand traditional medicine texts”. Faculty of Medicine Siriraj Hospital. Mahidol University 2552;(2).
Wagner H, Bladt. “Plant drug analysis: a thin layer chromatography atlas”. Newyork: Springer 1996.