Management and treatment outcome of patients with tuberculosis at Bankruad Hospital
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Abstract
Introduction: Tuberculosiswas an infectious disease which has been an important public health problemand cause of dead in many countries worldwide. Management of patients with tuberculosis including diagnosis andtreatment is the most important key for solving and controlling the disease. Objectives: To study the managementand the outcome in management of patients with tuberculosis at Bankruad Hospital, Buriram province. Materials andMethods: This study was retrospective observational study in new tuberculosis patients registered between October1, 2006 and September 30, 2009. The management system for tuberculosis patients composed of the providingclinical care and treatment of tuberculosis patients by the multidisciplinary team. Patients’ data including generalcharacteristic, diagnosis and treatment were collected from medical record. Descriptive statistics, Chi–square testand multiple logistic regression model were used for statistical analysis. Results: There were 124 patients recruitedinto the study, 83 males (66.9%) and 41 females (33.1%). One hundred and three patients (83.1%) hadpulmonarytuberculosis, 20 patients (16.1%) hadextra-pulmonary tuberculosis, and 1 patient (0.8%) had pulmonary tuberculosiswith extra-pulmonary tuberculosis. Most of patients hadfollowingdata; 71 patients (57.3%) with positive sputumtest, 90 patients (72.6%) with chest X-ray found infiltration, and 107 patients (86.3%) with negative HIV test. Onehundred and eight patients (87.1%) were treated with 2HRZE(S)/4HR regimen. The major drug related problemwas inappropriate dosage regimen found in 68 patients (54.8%) followed by adverse drug reaction found in 19patients (15.3%). Most of patients, 114 patients (91.9%) had good compliance and 112 patients (90.3%) were treatedsuccessfully. Data analysis showed that positive HIV test, suptherapeutic dose of rifampicin and non-compliancewere associated with poor treatment outcome. Conclusion: Management of patients with tuberculosis at BankruadHospital was consistent with the National Tuberculosis Program (NTP) and the high treatment success.
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