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Introduction: Herb is the hope for many people who want self-reliance in the treatment of diseases to substitute for modern medicines. However, there are many obstacles in the use of herbal medicines particular the variation of the quality of the raw materials, the species and the used part of the herb. The confusion is also from homonym of the herbs special the herbs which have similar external characteristics. Objectives: To investigate the species of Chan-daeng dried wood powder marketed in the wholesale herbal stores in Bangkok and vicinity areas whether is Pterocarpus santalinus L.f. wood or Dracaena cochinchinensis (Lour.) S.C.Chen wood. Method: The samples were purchased by asking in Thai common name of the herb as Chan-daeng from the herbal wholesale stores in Bangkok and vicinity areas. The gradient elution, using HPLC coupled with a diode array detector was used for the separation. The information obtained from the chromatograms of the samples were compared to that of the known species herbs which were previously identified by pharmacognosy method. Results: The HPLC fingerprint obtained from Pterocarpus santalinus L.f. was significantly difference from that of Dracaena cochinchinensis (Lour.) S.C.Chen whereas the HPLC fingerprints obtained from all samples were similar to the HPLC fingerprint of Dracaena cochinchinensis (Lour.) S.C.Chen. Conclusion: All samples purchased in the name of Chan-daeng were Dracaena cochinchinensis (Lour.) S.C.Chen.
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