Clinical outcomes and quality of life of asthma patients in asthma clinic at a tertiary care hospital
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Abstract
Introduction: The objective of this study was to evaluate clinical outcomes and quality of life in asthma patients by multidisciplinary team in asthma clinic. Methods: This study was a retrospective quasi-experiment in out-patients who were newly diagnosed with asthma by the physicians and visited to the asthma clinic from October 2010 to January 2012. The patients were followed-up at the clinic for at least six months and received pharmaceutical care by pharmacists at least two times. The clinical outcomes were evaluated by patients’ lung function, and level of asthma control measured every two months. Patients’ quality of life (QOL) was determined at baseline and at 6 month after the treatment using Thai Mini Asthma quality of life questionnaire. Results: This study included 41 patients, mean age 44.00±5.32 year olds, 65.9 % had female. The average of peak expiratory flow rate (PEFR) was increasing from baseline (304.8±102.9 and 330.2 ± 114.2, respectively, p=0.026). The percentage of the patients with %PEFR above 80% were increasing from baseline compared to % PEFR at 6th month (41.5% and 61 %, respectively, p=0.003). The level of asthma control in patients were improved significantly (p=0.008). At baseline, the numbers of the patients with controlled and partly controlled/uncontrolled asthma were 34.2 % and 65.8 % respectively. At the end of study (6 months), patients with controlled asthma increased to 65.9% and patients with partly controlled/uncontrolled asthma decreased to 34.1% and the number of patient with asthma exacerbation decreased significantly (19.5 % and 2.4 %, p=0.039) The overall patients’ quality of life (mean±SD) were significantly improved from the baseline (4.1±0.9 and 5.2±1.0, respectively, p<0.0001) as well as every sub-dimensions; symptomatic, emotional, limitation in activity and environmental stimulation dimension. Conclusions: Management by a multidisciplinary team in the asthma clinic resulted in improving the patients’ quality of life and clinical outcome.
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