Implantable drug delivery systems: Implant technologies

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Sureewan Duangjit
Sureewan Bamrungthai
Tanasait Ngawhirunpat


Implantable drug delivery system is a modified release dosage form. To improve quality of life of patients, implants are alternative drug delivery systems. The crucial advantages of these drug delivery systems over conventional delivery systems (oral and parenteral dosage form) are direct delivery to target with a constant rate, low dose required for treatment, avoidance probable systemic side effects, probable to control of drug release, high efficacy of treatment and dose termination is possible. However, the limitations of these drug delivery systems are invasive, limit to potent drug, uncomfortable feeling and biocompatibility issues. Therefore, implantable drug delivery systems are still need to be developed to optimize the technology of several drug products and to enhance efficacy, safety and stability. The available types and technologies of implantable dosage form are the main focus of this review.

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