Fruits Anti-Cancer Drugs Interaction Treatment
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Abstract
Fruits are one kind of food which has been widely consumed. However, some fruits have reported altering the Cytochrome P450 enzyme and P-glycoprotein (P-gp). Fruit-drug interaction can occur when taken together. The list of fruits that have been reported to change the action of the enzymes and P-gp includes Grapefruit, Star fruit, Pineapple, and Pomelo. Thus, it might change cancer drug levels, affecting efficacy and adverse effect of treatment. Most data of fruit-drug interaction come from in vivo studies. Data of human clinical study is limited. However, the available data can be applied to monitoring adverse drug reactions of anti-cancer medications, pharmaceutical care in cancer patients, and providing information about consuming fruits safely in patients undergoing systemic medicines for cancers.
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References
Ali, Y., Shams, T., Wang, K., Cheng, Z., Li, Y., Shu, W., et al. (2020). The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions. Chinese Medicine, 15(1), 71.
Amadi, C., & Lemon, K. (2018). Effect of pineapple (Ananas comomsus) and uziza (Piper guineense) extracts on fexofenadine bioavailability : posibile role of p-glyciprotein (P-GP) and organic anion transportering polypeptides (OATPS). Int Res J Pharm, 9, 17-21.
Anlamlert, W., Sermsappasuk, P., Yokubol, D., & Jones, S. (2015). Pomelo enhances cyclosporine bioavailability in healthy male Thai volunteers. J Clin Pharmacol, 55(4), 377-383.
Bailey, D. G., Arnold, J. M., Munoz, C., & Spence, J. D. (1993). Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin. Clin Pharmacol Ther, 53(6), 637-642.
Bailey, D. G., Arnold, J. M., Strong, H. A., Munoz, C., & Spence, J. D. (1993). Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics. Clin Pharmacol Ther, 54(6), 589-594.
Bjornsson, T. D., Callaghan, J. T., Einolf, H. J., Fischer, V., Gan, L., Grimm, S., et al. (2003). The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective. J Clin Pharmacol, 43(5), 443-469.
Chatuphonprasert, W., & Jarukamjorn, K. (2012). Impact of six fruits--banana, guava, mangosteen, pineapple, ripe mango and ripe papaya--on murine hepatic cytochrome P450 activities. J Appl Toxicol, 32(12), 994-1001.
Chieli, E., Romiti, N., Rodeiro, I., & Garrido, G. (2010). In vitro modulation of ABCB1/P-glycoprotein expression by polyphenols from Mangifera indica. Chem Biol Interact, 186(3), 287-294.
DuBuske, L. M. (2005). The role of p-glycoprotein and organic anion-transporting polypeptides in drug Interactions. Drug Safety, 28(9), 789-801.
Edwards, D. J., Fitzsimmons, M. E., Schuetz, E. G., Yasuda, K., Ducharme, M. P., Warbasse, L. H., et al. (1999). 6',7'-Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and p-glycoprotein. Clin Pharmacol Ther, 65(3), 237-244.
Fasinu, P. S., & Rapp, G. K. (2019). Herbal interaction with chemotherapeutic drugs—A focus on clinically significant findings. Frontiers in Oncology, 9(1356).
Fleisher, B., Unum, J., Shao, J., & An, G. (2015). Ingredients in fruit juices interact with dasatinib through inhibition of BCRP: a new mechanism of beverage-drug interaction. J Pharm Sci, 104(1), 266-275.
Grenier, J., Fradette, C., Morelli, G., Merritt, G. J., Vranderick, M., & Ducharme, M. P. (2006). Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans. Clin Pharmacol Ther, 79(3), 255-262.
Hanley, M. J., Masse, G., Harmatz, J. S., Cancalon, P. F., Dolnikowski, G. G., Court, M. H., et al. (2013). Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol, 75(4), 1041-1052.
Helmy, S. A., & El-Bedaiwy, H. M. (2020). Effect of pineapple juice on the pharmacokinetics of celecoxib and montelukast in humans. 11(5), 301-311.
Hidaka, M., Fujita, K.-i., Ogikubo, T., Yamasaki, K., Iwakiri, T., Okumura, M., et al. (2004). Potent inhibition by star fruit of human cytochrome P450 3A (CYP3A) activity. Drug Metabol Dispos, 32(6), 581-583.
Hidaka, M., Nagata, M., Kawano, Y., Sekiya, H., Kai, H., Yamasaki, K., et al. (2008). Inhibitory effects of fruit juices on cytochrome P450 2C9 activity in vitro. Biosci Biotechnol Biochem, 72(2), 406-411.
Hidaka, M., Okumura, M., Fujita, K., Ogikubo, T., Yamasaki, K., Iwakiri, T., et al. (2005). Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab Dispos, 33(5), 644-648.
Hsu, P.-W., Shia, C.-S., Lin, S.-P., Chao, P.-D. L., Juang, S.-H., & Hou, Y.-C. (2013). Potential risk of mulberry–drug Interaction: modulation on p-glycoprotein and cytochrome P450 3A. J Agr Food Chem, 61(18), 4464-4469.
Huang, S. M., Strong, J. M., Zhang, L., Reynolds, K. S., Nallani, S., Temple, R., et al. (2008). New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process. J Clin Pharmacol, 48(6), 662-670.
Ishihara, M., Toda, H., Sunagane, N., & Ohta, T. (2011). Furanocoumarins contents and cytochrome P450 3A (CYP3A) inhibitory activities of various processed fruit peel products: outflow of 6',7'-Dihydroxybergamottin during processing treatment of peel. Yakugaku Zasshi, 131(5), 679-684.
Kaneko, K., Suzuki, K., Iwadate-Iwata, E., Kato, I., Uchida, K., & Onoue, M. (2013). Evaluation of food-drug interaction of guava leaf tea. Phytother Res, 27(2), 299-305.
Lilja, J. J., Juntti-Patinen, L., & Neuvonen, P. J. (2004). Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol. Clin Pharmacol Ther, 75(3), 184-190.
Lilja, J. J., Raaska, K., & Neuvonen, P. J. (2005). Effects of orange juice on the pharmacokinetics of atenolol. Eur J Clin Pharmacol, 61(5-6), 337-340.
Malhotra, S., Bailey, D. G., Paine, M. F., & Watkins, P. B. (2001). Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther, 69(1), 14-23.
Oga, E. F., Sekine, S., & Horie, T. (2013). Ex vivo and in vivo investigations of the effects of extracts of Vernonia amygdalina, Carica papaya and Tapinanthus sessilifolius on digoxin transport and pharmacokinetics: assessing the significance on rat intestinal p-glycoprotein efflux. Drug Metab Pharmacokinet, 28(4), 314-320.
Pohl, C., Will, F., Dietrich, H., & Schrenk, D. (2006). Cytochrome P450 1A1 expression and activity in Caco-2 cells: modulation by apple juice extract and certain apple polyphenols. J Agric Food Chem, 54(26), 10262-10268.
Rashid, J., McKinstry, C., Renwick, A. G., Dirnhuber, M., Waller, D. G., & George, C. F. (1993). Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice. Br J Clin Pharmacol, 36(5), 460-463.
Reif, S., Nicolson, M. C., Bisset, D., Reid, M., Kloft, C., Jaehde, U., et al. (2002). Effect of grapefruit juice intake on etoposide bioavailability. Eur J Clin Pharmacol, 58(7), 491-494.
Rodeiro, I., José Gómez-Lechón, M., Perez, G., Hernandez, I., Herrera, J. A., Delgado, R., et al. (2013). Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes. Phytother Res, 27(5), 745-752.
Sridharan, K., & Sivaramakrishnan, G. (2016). Interaction of citrus juices with cyclosporine: systematic review and meta-analysis. Eur J Drug Metab Pharmacokinet, 41(6), 665-673.
Srinivas, N. R. (2013). Is pomegranate juice a potential perpetrator of clinical drug-drug interactions? Review of the in vitro, preclinical and clinical evidence. Eur J Drug Metab Pharmacokinet, 38(4), 223-229.
Takanaga, H., Ohnishi, A., Matsuo, H., & Sawada, Y. (1998). Inhibition of vinblastine efflux mediated by p-glycoprotein by grapefruit juice components in caco-2 cells. Biol Pharm Bull, 21(10), 1062-1066.
Tapaninen, T., Neuvonen, P. J., & Niemi, M. (2011). Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren. Br J Clin Pharmacol, 71(5), 718-726.
Valenzuela, B., Rebollo, J., Pérez, T., Brugarolas, A., & Pérez-Ruixo, J. J. (2011). Effect of grapefruit juice on the pharmacokinetics of docetaxel in cancer patients: a case report. Br J Clin Pharmacol, 72(6), 978-981.
van Erp, N. P., Baker, S. D., Zandvliet, A. S., Ploeger, B. A., den Hollander, M., Chen, Z., et al. (2011). Marginal increase of sunitinib exposure by grapefruit juice. Cancer Chemother Pharmacol, 67(3), 695-703.
Wen, F., Shi, M., Bian, J., Zhang, H., & Gui, C. (2016). Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol, 54(2), 293-302.
Xu, Y. X., Xiang, Z. B., Jin, Y. S., Xu, W., Sun, L. N., Chen, W. S., et al. (2016). Constituents from the roots of Actinidia chinensis and their cytochrome P450 enzyme inhibitory activities. Chem Biodivers, 13(11), 1454-1459.
Yin, O. Q., Gallagher, N., Li, A., Zhou, W., Harrell, R., & Schran, H. (2010). Effect of grapefruit juice on the pharmacokinetics of nilotinib in healthy participants. J Clin Pharmacol, 50(2), 188-194.
Yong, W. P., Desai, A. A., Innocenti, F., Ramirez, J., Shepard, D., Kobayashi, K., et al. (2007). Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer. Cancer Chemother Pharmacol, 60(6), 811-819.
Zhang, J. W., Liu, Y., Cheng, J., Li, W., Ma, H., Liu, H. T., et al. (2007). Inhibition of human liver cytochrome P450 by star fruit juice. J Pharm Pharm Sci, 10(4), 496-503.
Zhang, L., Reynolds, K. S., Zhao, P., & Huang, S. M. (2010). Drug interactions evaluation: an integrated part of risk assessment of therapeutics. Toxicol Appl Pharmacol, 243(2), 134-145.