Effects of Interactive Patient Education by Pharmacists via Line Application on Clinical Outcomes in Patients with Diabetes
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Abstract
At present, LINE application is widely used. Several previous studies have used applications for interventions in patients with diabetes. However, no studies have been conducted using the LINE application for intervention in diabetic patients instead of healthcare providers at hospitals, like a pharmacist. No additional information was given to patients at the hospital. Objective: to examine the effects of LINE application-based pharmacist intervention on clinical outcomes, diabetes knowledge, and medication adherence in patients with diabetes. Methods: The study was a randomized controlled trial. Samples were patients who received treatment in an outpatient diabetes clinic of a community hospital in Nakhon Si Thammarat Province. A total of 180 recruited patients were randomly allocated to one of two groups: the study group (n = 90) and the control group (n = 90). The study group received diabetes education via LINE application of mobile phone once a week for six months. No additional patient education was provided at the hospital. A patient could contact the pharmacist through the application if needed. The control group received usual care. Diabetic self-care guides were distributed to both groups. Results: The study group had significantly lower glycosylated hemoglobin (HbA1c) and fasting plasma glucose (FPG) levels than the control group at the end of the trial (HbA1c = 7.59 + 1.21% and 8.20 + 1.42%, respectively; P = 0.003 and FPG = 141.02 + 25.13 mg/dL and 163.27 + 47.32 mg/dL, respectively; P < 0.001). Lipid levels and blood pressure of the study group were not substantially different from those of the control group (P > 0.05). Diabetes knowledge and medication adherence scores in the study group were significantly greater than those in the control group (P < 0.001 and P = 0.003, respectively). Conclusion: The intervention by pharmacists through LINE application allows adults living with diabetes to control their sugar levels better, having increased knowledge about diabetes and medication adherence.
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References
Abaza H, Marschollek M. SMS education for the promotion of diabetes self-management in low & middle income countries: a pilot randomized controlled trial in Egypt. BMC Public Health 2017; 17(1): 962.
Adam L, O'Connor C, Garcia AC. Evaluating the impact of diabetes self-management education methods on knowledge, attitudes and behaviours of adult patients with type 2 diabetes mellitus. Can J Diabetes 2018; 42(5): 470-477.
Agarwal P, Mukerji G, Desveaux L, et al. Mobile app for improved self-management of type 2 diabetes: multicenter pragmatic randomized controlled trial. JMIR Mhealth Uhealth 2019; 7(1): e10321.
Almutairi N, Hosseinzadeh H, Gopaldasani V. The effectiveness of patient activation intervention on type 2 diabetes mellitus glycemic control and self-management behaviors: a systematic review of RCTs. Prim Care Diabetes 2020; 14(1): 12-20.
AlShayban DM, Naqvi AA, Alhumaid O, et al. Association of disease knowledge and medication adherence among out-patients with type 2 diabetes mellitus in Khobar, Saudi Arabia. Front Pharmacol 2020; 11: 60.
American Association of Diabetes Educators. AADE7 self-care behaviors. Diabetes Educ 2008; 34(3): 445-449.
American Diabetes Association. Standards of medical care in diabetes-2021. Diabetes Care 2021; 44(suppl 1): S1-179.
Avdal EU, Uran BNO, Pamuk G, et al. Investigation of the effect of web-based diabetes education on metabolic parameters in people with type 2 diabetes: a randomized controlled trial. J Infect Public Health 2020; 13(12): 1892-1898.
Bonn SE, Alexandrou C, Hjorleifsdottir Steiner K, et al. App-technology to increase physical activity among patients with diabetes type 2 - the DiaCert-study, a randomized controlled trial. BMC Public Health 2018; 18(1): 119.
Bukhsh A, Khan TM, Sarfraz Nawaz M, et al. Association of diabetes knowledge with glycemic control and self-care practices among Pakistani people with type 2 diabetes mellitus. Diabetes Metab Syndr Obes 2019; 12: 1409-1417.
Bukhsh A, Nawaz MS, Ahmed HS, et al. A randomized controlled study to evaluate the effect of pharmacist-led educational intervention on glycemic control, self-care activities and disease knowledge among type 2 diabetes patients: a consort compliant study protocol. Medicine 2018; 97(12): e9847.
Dermkhuntod N, Kwancharoen R, Chuantantikamol C, et al. Effects of telehealth monitoring on glycemic control and medication adherence in patients with poorly controlled type 2 diabetes. Vajira Med J 2021; 65(Suppl): S75-90.
Diabetes Association of Thailand. Clinical practice guideline for diabetes [Online]. 2014 [cited 2021 Nov 9]. Available from: https://www.diabassocthai.org.
Diabetes Association of Thailand. Diabetes situation [Online]. 2021 [cited 2021 Nov 9]. Available from: https://www.dmthai.org.
Division of Non-Communicable Diseases. Know your numbers & know your risks [Online]. 2020 [cited 2021 Nov 9]. Available from: http://thaincd.com/2016/media.php.
Division of Non-Communicable Diseases. Number and death rate from diabetes per 100,000 population [Online]. 2019 [cited 2021 Nov 9]. Available from: http://thaincd.com.
Florey CD. Sample size for beginners. BMJ 1993; 306: 1181–1184.
Goodarzi M, Ebrahimzadeh I, Rabi A, et al. Impact of distance education via mobile phone text messaging on knowledge, attitude, practice and self efficacy of patients with type 2 diabetes mellitus in Iran. J Diabetes Metab Disord 2012; 11(1): 10.
Gordon J, McEwan P, Idris I, et al. Treatment choice, medication adherence and glycemic efficacy in people with type 2 diabetes: a UK clinical practice database study. BMJ Open Diabetes Res Care. 2018; 6(1): e000512.
Graham, TP. Hypertension. In: Kellerman RD, Rakel DP, editors. Conn’s current therapy. Philadelphia: Elsevier; 2022. 123-130.
Hfocus News Agency. A serious lack of government pharmacists exists [Online]. 2017 [cited 2021 Nov 9]. Available from: https://www.hfocus.org/content/2017/09/14623.
Hochsmann C, Muller O, Ambuhl M, et al. Novel smartphone game improves physical activity behavior in type 2 diabetes. Am J Prev Med 2019; 57(1): 41-50.
Ibrahim AO, Agboola SM, Elegbede OT, et al. Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria. J Int Med Res 2021; 49(10): 1-13.
International Diabetes Federation. IDF diabetes atlas [Online]. 2019 [cited 2021 Nov 2]. Available from: https://www.diabetesatlas.org/en/.
Lee DY, Yoo SH, Min KP, et al. Effect of voluntary participation on mobile health care in diabetes management: randomized controlled open-label trial. JMIR Mhealth Uhealth 2020; 8(9): e19153.
Limrermsakul S, Saneha C, Wattanakitkrileart D, et al. Effects of a health literacy development program on self-care behaviors in the elderly with type 2 diabetes mellitus. Nurs Sci J Thail 2022; 40(1): 84-98.
LINE Application [Online]. 2017 [cited 2017 Jan 3]. Available from: https://linecorp.com
LINE Thailand. News in Thailand [Online]. 2021 [cited 2021 Nov 2]. Available from: https://linecorp.com/th/pr/news/th/2021/3904.
McMillan KA, Kirk A, Hewitt A, et al. A systematic and integrated review of mobile-based technology to promote active lifestyles in people with type 2 diabetes. J Diabetes Sci Technol 2017; 11(2): 299-307.
National Statistical Office. Percentage of population (aged 15 years and over) with mobile phones by region [Online]. 2021 [cited 2021 Nov 9]. Available from: https://data.go.th/dataset/535.
Shen Y, Wang F, Zhang X, et al. Effectiveness of internet-based interventions on glycemic control in patients with type 2 diabetes: meta-analysis of randomized controlled trials. J Med Internet Res 2018; 20(5): e172.
Silva-Tinoco R, Cuatecontzi-Xochitiotzi T, De la Torre-Saldaña V, et al. Influence of social determinants, diabetes knowledge, health behaviors, and glycemic control in type 2 diabetes: an analysis from real-world evidence. BMC Endocr Disord 2020; 20(1): 130.
Srina S. Development of care model for diabetic type 2 by Line application. J Res Health Innov Dev 2021; 2(1): 123-133.
Srisuk P, Methakanjanasak N. Effects of the internet based self-management program for carbohydrate control and exercise promotion among patients with type 2 diabetes. Udhhosmj 2022; 30(1): 12-23.
Sun B, Luo Z, Zhou J. Comprehensive elaboration of glycemic variability in diabetic macrovascular and microvascular complications. Cardiovasc Diabetol 2021; 20: 9.
Sun C, Sun L, Xi S, et al. Mobile phone-based telemedicine practice in older Chinese patients with type 2 diabetes mellitus: randomized controlled trial. JMIR Mhealth Uhealth 2019; 7(1): e10664.
Thai Hypertension Society. Thai guidelines on the treatment of hypertension [Online]. 2019 [cited 2021 Nov 9]. Available from: http://www.thaihypertension.org/guideline.html.
Wongwiwatthananukit S. Krittiyanunt S, Wannapinyo A. Development and validation of an instrument to assess the general knowledge of patients with diabetes. Thai J Pharm Sci 2004; 28: 17-29.
Zhang L, He X, Shen Y, et al. Effectiveness of smartphone app-based interactive management on glycemic control in Chinese patients with poorly controlled diabetes: randomized controlled trial. J Med Internet Res 2019; 21(12): e15401.