Gender differences in the metabolic syndrome screening using modified Thai Diabetes Risk Score

Abstract

Introduction: Diabetes risk score is a questionnaire which can be used for metabolic syndrome screening in clinical practice. This study aimed to test metabolic syndrome screening with the modified Thai Diabetes Risk Score in male and female. Materials and methods: This study was designed as a cross sectional analytical and analysed from computer database of special medical examination room, Srinagarind hospital, Khon Kaen between January 2007 and December 2009, aged 35-75 years. The data collection was performed only the first result and completed data of individuals attending checkup clinic included age, gender, waist circumference, body mass index, blood pressure, fasting blood glucose, triglyceride, and high density lipoprotein. The exclusion was done on incomplete data or previously diagnosed with dyslipidemia. The randomization of sample used statistical software SPSS for Windows version 16.0. The test of metabolic syndrome screening with the modified Thai Diabetes Risk Score was analyzed by receiver operating characteristic (ROC) of the modified Thai Diabetes Risk Score in male and female. The optimal cutoff point for metabolic syndrome screening in male and female was analyzed by statistical software STATA version 12.0. Results: The area under the ROC of the modified Thai Diabetes Risk Score in male and female were not different. Hence, the optimal cutoff point for metabolic syndrome screening in male and female were the same point (cutoff = 6 based on the score ranged from 0 to 13) with sensitivity 83.8 (95% Cl 79.2-87.6), specificity of 73.1(95% Cl 70.3-75.8), false positive rate of 26.9 (95% Cl 24.2-29.7), false negative rate of 116.2 (95%CI 12.4-20.8), PPV of 47.7 (95% Cl 43.4-52.0), NPV of 93.3 (95% Cl 92.0-95.4). 39.8% of patients need subsequent test to confirm diagnosis.