Adverse Drug Reaction Monitoring And Counseling in Oncologic Patients At Mahasarakham Hospital
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Abstract
The objectives of this study were to compare knowledge base of diseases, drug usage, adverse drug reactions and proper self-care in new and old cases of breast and colorectal cancer patients after receiving counseling. Moreover, adverse drug reactions (ADRs) of cancer chemotherapy were monitored. The study was conducted during 1 October 2010 to 30 January 2011 at Mahasarakham hospital.
in the study, fifty patients participated and twenty-one of them were new cases. Prior to counseling and monitoring about ADRs from chemotherapy, patients were assessed their self-knowledge. Results showed that between new and old cases, knowledge scores in both before and after counseling did not significantly difference (p=0.213 and p=0.415 respectively). After receiving counseling, both groups of patients had significantly increased in knowledge score (p<0.001).
Forty-six patients had ADRs (Seventeen patients in new case and twenty-nine patients in old cases). The most ADR found in breast cancer patients was alopecia which was 100% in old cases and 90% in new case. in colorectal cancer, the most adverse event was fatigue (45.4% in old cases and 58.3% in new cases). All of ADRs are non-serious events.
To be concluded, counseling improves knowledge of cancer patients who received chemotherapy.
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References
Colin DM, Cynthia BP, Alan DL and Christopher JM. Cancer incidence mortality and survival by site for 14 regions of the world. World Health Organization [internet], 2010 [cited 2010 Aug 23]: 18(13): [47 screens].
Jarunee janpraparn. Role of pharmacist in the prevention of potential adverse drug reaction and medication errors in ambulatory oncology patients. Mahidol university [internet]. 2007 [2010 June 26]; 1(1): [254screens]. Available: http://mulinetio.li.mahidol.ac.th/e-thesis/4737144.pdf
Surawajee Jangmuenwai., Pharmacist’s role in detecting and reducing adverse drug events of chemotherapy at outpatient pharmacist service. Maharat Nakhonratchasima hospital. Mahidol university [internet]. 2007 [2010 June 26]; 1(1): [254 screens].
Jessica A, Louise B, Eugenia c, vilma c, Ted G, Lamar M. et al. Breast Cancer Facts & Figures. American Cancer Society. Atlanta: Georgia; 2006. p. 1-28.
Mark GK, Paul GH, Mark RS, Petra F. Rebecca OS, James MK, et al. American Society of Clinical Oncology Guideline for Antiemetics in Oncology. ASCO [internet]. 2006 June 20 [cited 2010 Aug 23]; 18(24): [16 screens].
Pgn GD. Ba JS. Patients’ experiences of chemotherapy: side-effects associated with 5-fluorouracil folinic acid in the treatment of colorectal cancer. Journal of clinical nursing. 1998; 7: 371-379