Transition from Parenteral to Oral Antimicrobial Therapy for Bacterial Pneumonia at Srinagarind Hospital
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Abstract
Use of parenteral antimicrobial in patient who can take oral medicines is a common non-rational antimicrobial use. Transition from parenteral to oral medicine must be done appropriately. The aim of this study was to collect the data about antimicrobial transition and assess its consistency to practice guideline for pneumonia of the American Thoracic Society and the Infectious Disease Society of America. Methods: This retrospective, descriptive study was performed in hospitalized patient with bacterial pneumonia at Srinagarind Hospital during 1 October 2016 to 30 September 2017. Data were collected from in-patient medical record and analyzed using descriptive statistics. Results: There were 110 patients eligible in the study. Community-acquired pneumonia, hospital-acquired pneumonia and both were diagnosed in 69.1, 26.4 and 4.5% of patients, respectively. Antibiotic prescribing was appropriated according to clinical practice guideline in term of type (76.5%) and dosage regimen (90.4%). Transition from parenteral to oral antimicrobial therapy was classified as step-down therapy (78.2%), sequential therapy (17.3%) and switch therapy (4.5%) and complied with clinical practice guideline in term of antimicrobial type (97.3%) and dosage regimen (93.6%). About 94.5% of patients had clinical improvement at hospital discharge. Conclusions: Antimicrobial transition for patients with bacterial pneumonia almost complied with practice guidelines and most patients had good clinical outcomes at hospital discharge.
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