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The present research aims to develop the mouthwash formula from guava leaf extract for decreasing bad breath. Various flavoring and sweetening agents as well as preservatives were tested. The formula composing of peppermint, menthol, sorbitol, paraben concentrate, sodium benzoate, propylene glycol, glycerin, alcohol, sodium hydroxide and water has good physical properties. Normal volurnteers gave highest satisfaction in this mouthwash. The stability of this formular is good for 3 months storage.The precipitate and dark brown color of solution were observed at 4 months period. Storage at 45 °c seemed to make the monthwash contained lesser in tannin content than at 5 and 37 °c. This mouthwash is appropriate to further test for the prevention of bad breath in the volunteers.
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Apisariyakul A, Chaichana N, Yousak W. The pharmacological effect of quercetin isolated from the leaves of Psidium guajava (Myrtaceae) on isolated rat and guinea-pig ileum preparation. Thai J. Pharmacol. 1992; 35: 14-15.
Caceres A, Cano o, Samayoa B, Aguliar L. Plants used in Guatemala for the treatment of gastrointestinal disorder: I. screening of 84 plants against enterobacteria. J.Ethnopharmacol. 1990; 30:55-67.
Janes AD. Handbood of biologically active phytochemical and their activities. Library of Congress Cataloging, 1992.
Lutterodt GD. Inhibition of Microlax-induced experimental diarrhea with narcotic-like extracts of Psidium guajava leaf in rats. J. Ethnopharmacol 1992; 37: 151-157.
Lutterodt GD. Inhibition of gastrointestinal release of acetylcholine by quercetin as a possible mode of action of Psidium guajava leaves extracts in the treatment of acute diarrheal disease. J. Ethnopharmacol. 1988; 24: 235-247.
Makkar HPS, Bhcemmel M, Borowy NK, Becker K. Gracriwetric ditermination of tannins and Their correlations with chemical and partein precipitation methods. J-Sci Ford Agri 1993; 61: 161-165.
Oldjide OA, Awe so, Makinde JM. Pharmacolgical studies on the leaf of Psidium guajava. Fitoterapia 1999; 70: 25-31.
Rosenberg M. Bad breath, diagnosis and treatment. Univ. Toranto Dent J. 1990; 3: 7-11.
Tonzetich J. Production and origin of oral malodour : a review of mechanisms and method of analysis. J Periodont 1977; 48: 13-20.