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The purposes of this quasi-experimental research were to compare: 1) depression of bipolar disorder patients before and after received mindfulness-based cognitive therapy program, 2) depression between bipolar disorder patients who received mindfulness-based cognitive therapy program to those who received regular nursing care. The samples were 36 bipolar disorder patients at the outpatient of Psychiatric Hospital. They were randomly assigned into experimental group and control group with 18 subjects in each group by matching the gender, antidepressant drug and level of depression. The research instruments were: Mindfulness-based cognitive therapy program and Beck Depression Inventory – IA (BDI-IA) which translated to Thai version by Mukda Sriyoung (Sriyoung, 1979 as cited in Areekit, 2012). These instruments were tested for content validity by 5 professional experts. The reliability was .83. Data were analyzed using mean, standard deviation and t-test.
Major findings were as follows: Depression of bipolar disorder patients after receiving mindfulness-based cognitive therapy program was significantly lower than that before receiving program, at .05 level (t = 17.39, p = .00). Depression of bipolar disorder patients after receiving mindfulness-based cognitive therapy program was significantly lower than those who could not receive the program, at .05 level (t = 11.68 p = .00). Mindfulness-based cognitive therapy program was effective in reducing depression among bipolar disorder patients
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