ผลของการเปรียบเทียบการใช้คอร์พิทอลินอล 60 และน้ำมันดอกคำฝอยเพื่อป้องกันการเกิดแผลกดทับในผู้ป่วยเด็กภาวะวิกฤต : การวิจัยเชิงทดลองแบบสุ่มชนิดมีกลุ่มควบคุมแบบปกปิดสองทาง

Duangjai  Nakju; Supatra  Phoapant; Sriwanna  Thasanthiah; Teepatad Chintapanyakun; Rojjanee  Lertbunrian; Nattachai  Anantasit

Authors

Duangjai Nakju Faculty of Medicine, Ramathibodi Hospital, Ratchathewi, Bangkok, 10400, Thailand
Supatra Phoapant Faculty of Medicine, Ramathibodi Hospital, Ratchathewi, Bangkok, 10400, Thailand
Sriwanna Thasanthiah Faculty of Medicine, Ramathibodi Hospital, Ratchathewi, Bangkok, 10400, Thailand
Teepatad Chintapanyakun Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Rojjanee Lertbunrian Faculty of Medicine, Ramathibodi Hospital, Ratchathewi, Bangkok, 10400, Thailand
Nattachai Anantasit Faculty of Medicine, Ramathibodi Hospital, Ratchathewi, Bangkok, 10400, Thailand

Keywords:

corpitolinol 60, safflower oil, pressure injury, critically ill children

Abstract

The randomized controlled trial with double-blinded aimed to compare the effect of caring for pediatric patients with safflower oil versus Corpitolinol 60 on the rate of pressure injuries in new pediatric patients. The participants were critically ill children who were hospitalized in PICU, Ramathibodi Hospital. The block of four randomization technique, using computer, was applied to recruit the participants into the study. The participants were randomly assigned to the Corpitolinol60 group (n = 159) and the safflower oil group (n = 161). The Data collection used the record form, record form of the pressure injury, and Braden Q scale. The sensitivity and specificity of Braden Q score were .92 and .59, respectively. The area under the curve (AUC) was found as .84. Data were analyzed using descriptive statistics, Chi-square test, and Fisher exact test.

The results of study revealed that genders, ages, diagnosis, criteria of ICU admission, sedative drugs, vasoactive drugs, using ventilator, hypoxemia, enteral feeding, immobilization, defecation frequency, serum albumin, nutrition profile, length of stay in ICU, and Braden Q score were no statistically significant difference between both groups. Moreover, the rate of pressure injuries in new pediatric patients was no significant difference between Corpitolinol 60 and safflower oil. Therefore, safflower oil was non-inferior to Corpitolinol 60 in prevention of pressure injury among critically ill children.

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