Diabetes insipidus in dogs

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5-2023
Published: Nov 3, 2023
Keywords:
Diabetes insipidus Dogs AVP-D AVP-R Central DI Nephrogenic DI

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Naowarat Suthamnatpong
Department of Veterinary Pharmacology, Faculty of Veterinary Science, Chulalongkorn University
0000-0001-5559-7551
Aranya Ponpornpisit
Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University

Abstract

Diabetes insipidus (DI) is a disease that can be found in dogs. DI is characterized by polydipsia and polyuria with hypotonic urine. DI is classified into two main types: AVP-D (CDI) and AVP-R (NDI). Diagnosis of DI has been based on the modified water deprivation test and AVP response test. Desmopressin is recommended as the first-line treatment for AVP-D owing to its nature in AVP deficiency. Alternatively, thiazide diuretics can also be used. Treatment of both primary and secondary AVP-R (NDI) with desmopressin is not always effective because the reduced renal response to AVP. Therefore, thiazide diuretics such as chlorothiazide is currently recommended and may be used in combination with amiloride to reduce the risk of hypokalemia. The purpose of this review article is to provide the up-to-date information about the causes, symptoms, diagnosis and treatment of diabetes insipidus in dogs

Article Details

Issue
Vol. 33 No. 1 (2023): Jan-Jun 2023
Section
Review articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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