Shortening of Days Open by Modified Cosynch Protocol in Early Postpartum Dairy Cows
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Abstract
Objective: The objective was to compare effect of two hormonal treatment programs, the eight days Cosynch (Cos) and the eight days Cosynch + CIDR (CosCD), to control cows without any treatment on days open in early postpartum dairy cows.
Materials and Methods: Seventy four cross bred Holstein cows were selected into the study under criteria as follow, within 40 - 50 days postpartum, lactation number 2 to 4, body condition score between 2.5 - 3.5 (scale of 1 - 5), and never been inseminated. Cows were randomly assigned into one of the three groups; control group, Cos group, and CosCD group. Cows in the control group (n = 24) were inseminated after detection of natural estrus by the a.m.-p.m. rule. Cows in the Cos group (n = 25) received an intramuscularly injection (i.m.) of 10 µg GnRH (designated as day 0) followed by an injection (i.m.) of 500 µg of PGF2α on day 8. The second GnRH (10 µg) injection was given between 60 and 66 h post PGF2α with fixed-time insemination (TAI). Cows in the CosCD group (n =25) received the same treatment as those in the Cos group plus an insertion of CIDR (1.38 g of progesterone) during days 0 and 8. Blood samples were collected in all cows for progesterone assay on day 0 and again for cows in the treatment groups (Cos and CosCD) on days 8 and 21 post AI. The reproductive organs of every cow were examined on day 0 by transrectal ultrasonography and again on day 8 for cows in the treatment groups. Pregnancy status was determined by ultrasonography on day 30 after TAI and on day 60 by transrectal palpation. Cows returning to estrus before 30 days after TAI were re-inseminated by the a.m.-p.m. rule.
Results: The overall pregnancy rate after TAI of cows in Cos (12.0%) and CosCD groups (36.0%) were not significantly difference when compare with cows in control group (37.5%) (P = 0.08). However, the average days of calving to first AI of pregnancy cows in treatment groups (Cos = 54.0 ± 3.5 days, CosCD = 56.6 ± 2.6 days) were significantly (P < 0.01) shorter than that of cows in control group (99.6 ± 14.0 days). Furthermore, the days open of cows in treatment groups (Cos = 105.0 ± 14.9 days, CosCD = 96.0 ± 23.3 day) were significantly (P < 0.05) lower than that cows in control group (125.0 ± 22.0 days).
Conclusion: Recent study suggested that the use of modified Cosynch and modified Cosynch + CIDR protocols in early postpartum dairy cows was resulted in shorter days open compared to untreated control cows. The modified Cosynch + CIDR protocol provided a good response for anestrus and noncycling postpartum dairy cows.
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References
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