Transient global amnesia
Keywords:
Transient global amnesia, precipitate events, hippocampal areaAbstract
Transient global amnesia (TGA) is a sudden onset of anterograde amnesia and some retrograde amnesia. TGA spontaneously resolves within 4 to 6 hours and may last up to 24 hours. The etiology and pathophysiology of TGA remain unclear, although recent hypothesis suggests that TGA potentially resulted from venous congestion rather than arterial ischemia or seizure liked episode. Most TGA patients had attacks following certain precipitating events either from emotional or physical stress. The brain magnetic resonance imaging shows delayed diffuse restriction in hippocampal area which mostly appeared at 24 to 48 hours after symptom onset and not persistent. Currently, there is no specific treatment for TGA. Avoidance of precipitating events has been suggested. However, recurrence of TGA is uncommon and the long-term cognitive dysfunction is subsequently unchanged.
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