Ocular Ischemic Syndrome


  • ธัญญทัต ผดุงเกียรติสกุล Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok


carotid artery occlusion, carotid artery imaging, chronic ocular hypoperfusion, ocular ischemic syndrome


Ocular ischemic syndrome (OIS) is a rare, but visual-threatening, condition comprise of a spectrum of clinical findings resulting from chronic ocular hypoperfusion. Establishing an accurate diagnosis is challenging due to its variable presentations. OIS usually signifies underlying carotid occlusive disease and may be its sole clinical presentation. Other etiologies that cause reduce blood flow to the orbital area may also responsible for OIS. Majority of the patients experience visual loss and orbital pain. Ocular manifestations include iris neovascularization, iris atrophy and characteristic posterior segment findings such as dilated retinal veins, mid-periphery retinal hemorrhages, microaneurysms and optic disc neovascularization. Carotid artery imaging and fundus fluorescein angiography assist establishing the diagnosis of ocular ischemic syndrome. Apart from ocular manifestations, affected patients are also at risk for cerebral and cardiovascular morbidities. Timely diagnosis and proper multidisciplinary team treatment are crucial not only to visual prognosis but also to patient survival. This review article presents the current knowledge on ocular ischemic syndrome.


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How to Cite

ผดุงเกียรติสกุล ธ. Ocular Ischemic Syndrome. J Thai Stroke Soc [Internet]. 2019 Apr. 29 [cited 2024 Jun. 14];18(1):42-58. Available from: https://he01.tci-thaijo.org/index.php/jtss/article/view/187479



Review article