OXIDATIVE STRESS IN ACUTE ISCHEMIC STROKE

Authors

  • Sombat Muengtaweepongsa Division of Neurology Faculty of Medicine Thammasat University

Abstract

Interruption of focal cerebral blood flow causes ischemic injuries to local brain tissue. The mechanism of ischemic injury, so-call ischemic cascade, is a primary damage. The primary injury leads to tissue necrosis then apoptosis. Secondary injury begins when ischemic tissue is reperfused. This secondary damage adds up the injuries to not only ischemic tissue but also surrounding normal tissue. Oxidative stress plays the major role in reperfusion injury. Neuroprotective therapies that intervened with mechanism of oxidative stress may show beneficial results in treatment of acute ischemic stroke

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Published

2019-02-19

How to Cite

1.
Muengtaweepongsa S. OXIDATIVE STRESS IN ACUTE ISCHEMIC STROKE. J Thai Stroke Soc [Internet]. 2019 Feb. 19 [cited 2024 Jun. 14];13(3):85-9. Available from: https://he01.tci-thaijo.org/index.php/jtss/article/view/173166

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Original article