Migraine and Stroke


  • เพชรรัตน์ ดุสิตานนท์ งานประสาทวิทยา ภาควิชาอายุรศาสตร์ โรงพยาบาลราชวิถี


migraine, stroke, migraine without aura, migraine with aura, ischemic stroke, hemorrhagic stroke


Migraine and stroke may be related. From epidemiological data, patients who had migraine with aura had 2-fold increased risk of ischemic stroke and 1.5 fold increased risk of hemorrhagic stroke. Several hypotheses explained the association between both conditions including polymorphism of many genes, thrombophilia factors, abnormal vascular reactivity, cortical spreading depression and increased risk factors for cardiovascular diseases. Patient with migraine with aura were associated with increased deep white matter hyperintensities and usually had multiple lesions. Differential diagnosis between aura of migraine and transient ischemic attack is difficult in some patients. If the diagnosis is uncertain, physical examination and further investigations are recommended. Aspirin is indicated when thrombosis is found. Management of ischemic stroke patients who also had migraine is the same as other ischemic stroke patients. Migraine without aura patients were not associated with increased risk of stroke or slightly increased, so there is no specific treatment other than acute and preventive treatment for migraine when there is indication. For migraine with aura patients, search for modified cardiovascular risk factors and manage those risks.


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How to Cite

ดุสิตานนท์ เ. Migraine and Stroke. J Thai Stroke Soc [Internet]. 2019 Aug. 24 [cited 2024 Jun. 19];15(2):82-104. Available from: https://he01.tci-thaijo.org/index.php/jtss/article/view/172123



Original article