Targeted Temperature Management in Critical care Neurology

Authors

  • Supaporn Konmun Faculty of Medicine, Thammasat University
  • Sornsawan Sriratanaporn Faculty of Medicine, Thammasat University
  • Sorapat Kitti-udom Faculty of Medicine, Thammasat University
  • Sombat Muengtaweepongsa Faculty of Medicine, Thammasat University

Keywords:

Targeted temperature management, Neuroprotective therapy, hypoxic-ischemic cascade, Intracranial pressure, Surface cooling, Endovascular cooling

Abstract

Two major objectives of targeted temperature management (TTM) in critical care neurology are to provide neuroprotective treatment and to control intracranial pressure (ICP). TTM is the most promising neuroprotective therapy due to its multiple sites of action against hypoxic-ischemic cascade. TTM is useful for ICP reduction. Hypoxic-ischemic brain damage and elevated ICP are common catastrophic conditions in critical care neurology. Two most reliable methods using in clinical practice and clinical trials are invasive endovascular technique and non-invasive surface cooling. Rapid induction, smooth sustainment and gradual rewarming are the important steps to achieve perfect TTM. Shivering is the most important physiologic response found during the process of TTM. Several randomized control trials have indicated that TTM gives favorable outcomes in patients with post-cardiac arrest syndrome (PCAS). Although TTM shows very promising results in pre-clinical studies, its clinical use in patients with ischemic stroke and traumatic brain injury is still controversial. TTM can apply to various clinical conditions associated with hypoxic-ischemic brain injury and elevated ICP in critical care neurology.

References

Hypothermia after Cardiac Arrest Study G. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002;346(8):549-56.

Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002;346(8):557-63.

Nunnally ME, Jaeschke R, Bellingan GJ, Lacroix J, Mourvillier B, Rodriguez-Vega GM, et al. Targeted temperature management in critical care: a report and recommendations from five professional societies. Crit Care Med. 2011;39(5):1113-25.

Mayer SA, Sessler DI, editors. Therapeutic hypothermia. New York: Marcel Dekker; 2005.

Polderman KH. Application of therapeutic hypothermia in the ICU: opportunities and pitfalls of a promising treatment modality. Part 1: Indications and evidence. Intensive Care Med. 2004;30(4):556-75.

Nolan JP, Morley PT, Vanden Hoek TL, Hickey RW, Kloeck WG, Billi J, et al. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced
life support task force of the International Liaison Committee on Resuscitation. Circulation. 2003;108(1):118-21.

Peberdy MA, Callaway CW, Neumar RW, Geocadin RG, Zimmerman JL, Donnino M, et al. Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010;122(18 Suppl 3):S768-86.

Callaway CW, Donnino MW, Fink EL, Geocadin RG, Golan E, Kern KB, et al. Part 8: Post-Cardiac Arrest Care: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2015;132(18 Suppl 2):S465-82.

Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VR, Deakin CD, et al. European Resuscitation Council and European Society of Intensive Care Medicine 2015 guidelines for post-resuscitation care. Intensive Care Med. 2015.

Hazinski MF, Nolan JP, Aickin R, Bhanji F, Billi JE, Callaway CW, et al. Part 1: Executive Summary: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2015;132(16 Suppl 1):S2-39.

Kurtz P, Fitts V, Sumer Z, Jalon H, Cooke J, Kvetan V, et al. How does care differ for neurological patients admitted to a neurocritical care unit versus a general
ICU? Neurocrit Care. 2011;15(3):477-80.

Sadaka F, Veremakis C. Therapeutic hypothermia for the management of intracranial hypertension in severe traumatic brain injury: a systematic review.
Brain Inj. 2012;26(7-8):899-908.

Corry JJ. The use of targeted temperature management for elevated intracranial pressure. Curr Neurol Neurosci Rep. 2014;14(6):453.

Muengtaweepongsa S. Methods and clinical applications of targeted temperature management. Neurology Asia. 2015;20(4): 325-33.

Gusev EISVI. Brain ischemia. New York: Kluwer Academic/Plenum Publishers; 2003.

Zhao H, Kilgas S, Alam A, Eguchi S, Ma D. The Role of Extracellular Adenosine Triphosphate in Ischemic Organ Injury. Crit Care Med. 2016;44(5):1000-12.

Xing C, Arai K, Lo EH, Hommel M. Pathophysiologic cascades in ischemic stroke. Int J Stroke. 2012;7(5):378-85.

Stead SM, Daube JR. Basics of Neurophysiology. Clinical Neurophysiology. 2016:3-29.

Hinkle JL, Bowman L. Neuroprotection for ischemic stroke. The Journal of neuroscience nursing : journal of the American Association of Neuroscience
Nurses. 2003;35(2):114-8.

Bennett MV, Pellegrini-Giampietro D, Gorter J, Aronica E, Connor J, Zukin RS, editors. The GluR2 hypothesis: Ca++-permeable AMPA receptors in delayed
neurodegeneration. Cold Spring Harbor symposia on quantitative biology; 1996: Cold Spring Harbor Laboratory Press.

Labiche LA, Grotta JC. Clinical trials for cytoprotection in stroke. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics.
2004;1(1):46-70.

Hazell AS. Excitotoxic mechanisms in stroke: an update of concepts and treatment strategies. Neurochemistry international. 2007;50(7-8):941-53.

Aronowski J, Strong R, Grotta JC. Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats. Journal of Cerebral Blood Flow & Metabolism. 1997;17(10):1048-56.

Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nature medicine. 2011;17(7):796-808.

Xi G, Keep RF, Hoff JT. Pathophysiology of brain edema formation. Neurosurgery Clinics of North America. 2002;13(3):371-83.

Strbian D, Durukan A, Pitkonen M, Marinkovic I, Tatlisumak E, Pedrono E, et al. The blood–brain barrier is continuously open for several weeks following transient
focal cerebral ischemia. Neuroscience. 2008;153(1):175-81.

Muengtaweepongsa S, Srivilaithon W. Targeted temperature management in neurological intensive care unit. World journal of methodology. 2017;7(2):55-67.

Monro A, editor. Observations on the structure and function of the nervous system. . Edinburgh: Creech & Johnson; 1783.

Kelly G, editor. “Appearances observed in the dissection of two individuals; death from cold and congestion of the brain”: Trans Med Chir Sci Edinb; 1824.

Neff S, Subramaniam RP. Monro-Kellie doctrine. J Neurosurg. 1996;85(6):1195.

Mokri B. The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology. 2001;56(12):1746-8.

Kincaid MS, Lam AM. MONITORING AND MANAGING INTRACRANIAL PRESSURE. Continuum. 2006;12(1):16.

Sheth K, McCullough M, Kazmi S, Lazaridis C, O’Phelan K, Shepherd SA, et al. Cerebral Herniation Syndromes and Intracranial Hypertension: Rutgers University Press; 2016.

Villa F, Citerio G. Intracranial pressure monitoring. Oxford Textbook of Neurocritical Care. 2016:107.

Polderman KH. Mechanisms of action, physiological effects, and complications of hypothermia. Critical Care Medicine. 2009;37(Supplement):S186-S202.

Talma N, Kok WF, de Veij Mestdagh CF, Shanbhag NC, Bouma HR, Henning RH. Neuroprotective hypothermia – Why keep your head cool during ischemia and
reperfusion. Biochimica et Biophysica Acta (BBA) - General Subjects. 2016;1860(11, Part A):2521-8.

Madathil RJ, Hira RS, Stoeckl M, Sterz F, Elrod JB, Nichol G. Ischemia reperfusion injury as a modifiable therapeutic target for cardioprotection or neuroprotection in patients undergoing cardiopulmonary resuscitation. Resuscitation. 2016;105:85-91.

Erecinska M, Thoresen M, Silver IA. Effects of hypothermia on energy metabolism in mammalian central nervous system. Journal of Cerebral Blood Flow & Metabolism. 2003;23(5):513-30.

Gonzalez-Ibarra FP, Varon J, Lopez-Meza EG. Therapeutic Hypothermia: Critical review of the molecular mechanisms of action. Frontiers in Neurology. 2011;2.

Chi OZ, Liu X, Weiss HR. Effects of mild hypothermia on blood–brain barrier disruption during isoflurane or pentobarbital anesthesia. Anesthesiology. 2001;95(4):933-8.

Schwab S, Georgiadis D, Berrouschot J, Schellinger PD, Graffagnino C, Mayer SA. Feasibility and safety of moderate hypothermia after massive hemispheric
infarction. Stroke. 2001;32(9):2033-5.

Seule MA, Muroi C, Mink S, Yonekawa Y, Keller E. Therapeutic hypothermia in patients with aneurysmal subarachnoid hemorrhage, refractory intracranial hypertension, or cerebral vasospasm. Neurosurgery. 2009;64(1):86-93.

Park CK, Jun SS, Kim MC, Kang JK. Effects of systemic hypothermia and selective brain cooling on ischemic brain damage and swelling. Acta Neurochir Suppl.
1998;71:225-8.

Kawai N, Nakamura T, Okauchi M, Nagao S. Effects of hypothermia on intracranial pressure and brain edema formation: studies in a rat acute subdural hematoma model. J Neurotrauma. 2000;17(3):193-202.

Suwannakin A, Muengtaweepongsa S. Initial experience of therapeutic hypothermia after cardiac arrest with surface cooling method in Thammasat Chalerm Prakiat Hospital: Two cases report. . J Med Assoc Thai 2011;94(Suppl. 7):S190-2.

P i n i c h j i n d a s u p A , H o m v i s e s B , Muengtaweepongsa S. Therapeutic Hypothermia with Extracorporeal Membrane Oxygenation (ECMO) and
Surface Cooling in Post-Cardiac Arrest Patients: 4 Case Reports. Journal of the Medical Association of Thailand. 2014;97(8):223.

Polderman K. Application of therapeutic hypothermia in the intensive care unit. Opportunities and pitfalls of a promising treatment modality - Part 2: practical aspects and side effects. Intensive CareMed. 2004;30:757 - 69.

Polderman KH, Rijnsburger ER, Peerdeman SM, Girbes ARJ. Induction of hypothermia in patients with various types of neurologic injury with use of large volumes of ice-cold intravenous fluid*. Critical Care Medicine. 2005;33(12):2744-51 10.1097/01. CCM.0000190427.88735.19.

Bernard S, Buist M, Monteiro O, Smith K. Induced hypothermia using large volume, ice-cold intravenous fluid in comatose survivors of out-of-hospital cardiac arrest: a preliminary report. Resuscitation. 2003;56(1):9-13.

Wang H, Olivero W, Lanzino G, Elkins W, Rose J, Honings D, et al. Rapid and selective cerebral hypothermia achieved using a cooling helmet. Journal of
neurosurgery. 2004;100(2):272-7.

Madden LK, Hill M, May TL, Human T, Guanci MM, Jacobi J, et al. The Implementation of Targeted Temperature Management: An Evidence-Based Guideline from the Neurocritical Care Society. Neurocrit Care. 2017.

Al-Senani FM, Graffagnino C, Grotta JC, Saiki R, Wood D, Chung W, et al. A prospective, multicenter pilot study to evaluate the feasibility and safety of using
the CoolGard (TM) System and Icy (TM) catheter following cardiac arrest. Resuscitation. 2004;62(2):143-50.

Lyden PD, Allgren RL, Ng K, Akins P, Meyer B, Al-Sanani F, et al. Intravascular Cooling in the Treatment of Stroke (ICTuS): Early Clinical Experience. Journal
of Stroke and Cerebrovascular Diseases. 2005;14(3):107-14.

Choi HA, Ko S-B, Presciutti M, Fernandez L, Carpenter AM, Lesch C, et al. Prevention of shivering during therapeutic temperature modulation: the Columbia anti-shivering protocol. Neurocritical care. 2011;14(3):389-94.

De Georgia MA, Krieger DW, Abou-Chebl A, Devlin TG, Jauss M, Davis SM, et al. Cooling for Acute Ischemic Brain Damage (COOL AID): a feasibility trial
of endovascular cooling. Neurology. 2004;63(2):312-7.

Lyden PD, Hemmen TM, Grotta J, Rapp K, Raman R. Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol. International Journal
of Stroke. 2014;9(1):117-25.

Worp HB, Macleod MR, Bath PM, Demotes J, Durand-Zaleski I, Gebhardt B, et al. EuroHYP-1: European multicenter, randomized, phase III clinical trial of
therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke. International Journal of Stroke. 2014.

Krieger DW, De Georgia MA, Abou-Chebl A, Andrefsky JC, Sila CA, Katzan IL, et al. Cooling for acute ischemic brain damage (cool aid): an open pilot study of induced hypothermia in acute ischemic stroke. Stroke. 2001;32(8):1847-54.

Fischer M, Lackner P, Beer R, Helbok R, Pfausler B, Schneider D, et al. Cooling Activity is Associated with Neurological Outcome in Patients with Severe
Cerebrovascular Disease Undergoing Endovascular Temperature Control. Neurocritical care. 2015;23(2):1-5.

Oh SH, Oh JS, Kim YM, Park KN, Choi SP, Kim GW, et al. An observational study of surface versus endovascular cooling techniques in cardiac arrest patients:
a propensity-matched analysis. Crit Care. 2015;19:85.

Seder DB, Van der Kloot TE. Methods of cooling: practical aspects of therapeutic temperature management. Crit Care Med. 2009;37(7 Suppl):S211-22.

Glover GW, Thomas RM, Vamvakas G, Al-Subaie N, Cranshaw J, Walden A, et al. Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data. Crit Care. 2016;20(1):381.

Uray T, Sterz F, Janata A, Wandaller C, Holzer M, Laggner AN, et al. Surface cooling with a new cooling-blanket for rapid induction of mild hypothermia in
humans after cardiac arrest: A feasibility trial. Circulation. 2006;114(18):1190-.

Dhaese HL, Martens PR, Muller NH, Casier IM, Mulier JP, Heytens L. The use of emergency medical cooling system pads in the treatment of malignant hyperthermia. Eur J Anaesthesiol. 2010;27(1):83-5.

CritiCool Specification M, (Rehovot, Israel). 510K for CritiCool system http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/denovo.cfm?ID=DEN140018 [updated01/23/2017. Available from: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/denovo.cfm?ID=DEN140018.

Hegazy A, Lapierre D, Althenayan E. Targeted temperature management after cardiac arrest and fever control with an esophageal cooling device. Critical Care.
2015;19(Suppl 1):P424.

Polderman KH. Application of therapeutic hypothermia in the intensive care unit. Opportunities and pitfalls of a promising treatment modality--Part 2: Practical aspects and side effects. Intensive Care Med. 2004;30(5):757-69.

Nair SU, Lundbye JB. The occurrence of shivering in cardiac arrest survivors undergoing therapeutic hypothermia is associated with a good neurologic outcome.
Resuscitation. 2013;84(5):626-9.

Presciutti M, Bader MK, Hepburn M. Shivering management during therapeutic temperature modulation: nurses’ perspective. Critical Care Nurse. 2012;32(1):33-42.

Logan A, Sangkachand P, Funk M. Optimal management of shivering during therapeutic hypothermia after cardiac arrest. Crit Care Nurse. 2011;31(6):e18-30.

Clifton GL, Miller ER, Choi SC, Levin HS, McCauley S, Smith KR, Jr., et al. Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med.
2001;344(8):556-63.

Thomsen JH, Hassager C, Bro-Jeppesen J, Soholm H, Nielsen N, Wanscher M, et al. Sinus bradycardia during hypothermia in comatose survivors of out-of-hospital cardiac arrest - a new early marker of favorable outcome? Resuscitation. 2015;89:36-42.

Muengtaweepongsa S, Jantanukul A, Suwanprasert K. Should the heart rate including the heart rate variability be important prognostigators in cardiac arrest?
Resuscitation. 2016;98:E15-E.

Srivilaithon W, Muengtaweepongsa S. The Outcomes of Targeted Temperature Management After Cardiac Arrest at Emergency Department: A Real-World
Experience in a Developing Country. Therapeutic hypothermia and temperature management. 2016.

Varon J, Acosta P. Therapeutic hypothermia: past, present, and future. Chest. 2008;133(5):1267-74.

Soeholm H, Kirkegaard H. Serum Potassium Changes During Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest-Should It Be Treated? Therapeutic hypothermia and temperature management. 2012;2(1):30-6.

Bernard SA, Buist M. Induced hypothermia in critical care medicine: a review. Crit Care Med. 2003;31(7):2041-51.

Lehot JJ, Piriz H, Villard J, Cohen R, Guidollet J. Glucose homeostasis. Comparison between hypothermic and normothermic cardiopulmonary bypass.
Chest. 1992;102(1):106-11.

Gagnon DJ, Nielsen N, Fraser GL, Riker RR, Dziodzio J, Sunde K, et al. Prophylactic antibiotics are associated with a lower incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management. Resuscitation. 2015;92:154-9.

Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Bottiger BW, et al. Postcardiac arrest syndrome: epidemiology, p a t h o p h y s i o l o g y , t r e a t m e n t , a n dprognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation. 2008;79(3):350-79.

Bro-Jeppesen J, Kjaergaard J, Stammet P, Wise MP, Hovdenes J, Aneman A, et al. Predictive value of interleukin-6 in postcardiac arrest patients treated with targeted temperature management at 33 degrees C or 36 degrees C. Resuscitation. 2016;98:1-8.

Adrie C, Laurent I, Monchi M, Cariou A, Dhainaou JF, Spaulding C. Postresuscitation disease after cardiac arrest: a sepsis-like syndrome? Current opinion in critical care. 2004;10(3):208-12.

Adrie C, Adib-Conquy M, Laurent I, Monchi M, Vinsonneau C, Fitting C, et al. Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like”
syndrome. Circulation. 2002;106(5):562-8.

Laver S, Farrow C, Turner D, Nolan J. Mode of death after admission to an intensive care unit following cardiac arrest. Intensive Care Med. 2004;30(11):2126-8.

Gunn AJ, Thoresen M. Hypothermic neuroprotection. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics. 2006;3(2):154-69.

Holzer M, Bernard SA, Hachimi-Idrissi S, Roine RO, Sterz F, Mullner M. Hypothermia for neuroprotection after cardiac arrest: systematic review and individual patient data meta-analysis. Crit Care Med. 2005;33(2):414-8.

Froehler MT, Geocadin RG. Hypothermia for neuroprotection after cardiac arrest: mechanisms, clinical trials and patient care. J Neurol Sci. 2007;261(1-2):118-26

Arrich J, Holzer M, Herkner H, Mullner M. Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation. C o c h r a n e D a t a b a s e S y s t R e v . 2009(4):CD004128.

Nielsen N, Wetterslev J, al-Subaie N, Andersson B, Bro-Jeppesen J, Bishop G, et al. Target Temperature Management after out-of-hospital cardiac arrest--a
randomized, parallel-group, assessorblinded clinical trial--rationale and design. American heart journal. 2012;163(4):541-8.

Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, et al. Targeted temperature management at 33 degrees C versus 36 degrees C after cardiac arrest. N Engl J Med. 2013;369(23):2197-206.

Cronberg T, Lilja G, Horn J, Kjaergaard J, Wise MP, Pellis T, et al. Neurologic Function and Health-Related Quality of Life in Patients Following Targeted
Temperature Management at 33 degrees C vs 36 degrees C After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA neurology. 2015;72(6):634-41.

Targeted Temperature Management after Cardiac Arrest. New England Journal of Medicine. 2014;370(14):1356-61.

Rittenberger JC, Callaway CW. Temperature Management and Modern Post–Cardiac Arrest Care. New England Journal of Medicine. 2013;369(23):2262-3.

Dumas F, Grimaldi D, Zuber B, Fichet J, Charpentier J, Pène F, et al. Is hypothermia after cardiac arrest effective in both shockable and nonshockable patients?
Insights from a large registry. Circulation. 2011;123(8):877-86.

Chan PS, Berg RA, Tang Y, Curtis LH, Spertus JA. Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest. Jama.
2016;316(13):1375-82.

Arrich J, Holzer M, Havel C, Mullner M, Herkner H. Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation. Cochrane Database Syst Rev. 2016;2:CD004128.

Moler FW, Silverstein FS, Meert KL, Clark AE, Holubkov R, Browning B, et al. Rationale, timeline, study design, and protocol overview of the therapeutic hypothermia after pediatric cardiac arrest trials. Pediatr Crit Care Med. 2013;14(7):e304-15.

Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, et al. Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children. New England Journal of Medicine. 2015;372(20):1898-908.

Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, et al. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. N Engl J Med. 2017;376(4):318-29.

van der Worp HB, Sena ES, Donnan GA, Howells DW, Macleod MR. Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis. Brain. 2007;130(12):3063-74.

van der Worp HB, Macleod MR, Kollmar R. Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials&quest. Journal of
Cerebral Blood Flow & Metabolism. 2010;30(6):1079-93.

Hemmen TM, Raman R, Guluma KZ, Meyer BC, Gomes JA, Cruz-Flores S, et al. Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke (ICTuS-L): Final Results. Stroke. 2010;41(10):2265-70.

Lyden P, Hemmen T, Grotta J, Rapp K, Ernstrom K, Rzesiewicz T, et al. Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2). Stroke.
2016;47(12):2888-95.

Tang XN, Liu L, Koike MA, Yenari MA. Mild hypothermia reduces tissue plasminogen activator-related hemorrhage and blood brain barrier disruption after
experimental stroke. Therapeutic hypothermia and temperature management. 2013;3(2):74-83.

Hong JM, Lee JS, Song HJ, Jeong HS, Choi HA, Lee K. Therapeutic hypothermia after recanalization in patients with acute ischemic stroke. Stroke. 2014;45(1):134-40.

van der Worp HB, Macleod MR, Bath PM, Demotes J, Durand-Zaleski I, Gebhardt B, et al. EuroHYP-1: European multicenter, randomized, phase III clinical trial of
therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke. Int J Stroke. 2014;9(5):642-5.

Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJ, Demaerschalk BM, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke:
A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2013.

Wijdicks EFM, Sheth KN, Carter BS, Greer DM, Kasner SE, Kimberly WT, et al. Recommendations for the Management of Cerebral and Cerebellar Infarction With
Swelling: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2014.

Murtha LA, McLeod DD, Pepperall D, McCann SK, Beard DJ, Tomkins AJ, et al. Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy. J Cereb Blood Flow Metab. 2015;35(4):592-600.

Dietrich WD, Alonso O, Busto R, Globus MY-T, Ginsberg MD. Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat. Acta neuropathologica. 1994;87(3):250-8.

Jiang JY, Lyeth BG, Kapasi M, Jenkins L, Povlishock J. Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat.
Acta neuropathologica. 1992;84(5):495-500.

Gu X, Wei ZZ, Espinera A, Lee JH, Ji X, Wei L, et al. Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats. Experimental
Neurology. 2015;267(0):135-42.

Zhi D, Zhang S, Lin X. Study on therapeutic mechanism and clinical effect of mild hypothermia in patients with severe head injury. Surg Neurol. 2003;59(5):381-5.

Jiang J, Yu M, Zhu C. Effect of long-term mild hypothermia therapy in patients with severe traumatic brain injury: 1 year follow up review of 87 cases. J Neurosurg.
2000;93:546 - 9.

Henderson W, Dhingra V, Chittock D, Fenwick J, Ronco J. Hypothermia in the management of traumatic brain injury: a systematic review and meta-analysis.
Intensive Care Med. 2003;29:1637 - 44.

Peterson K, Carson S, Cairney N. Hypothermia treatment for traumatic brain injury: a systematic review and metaanalysis. J Neurotrauma. 2008;25:62 - 71.

McIntyre L, Fergusson D, Hebert P, Moher D, Hutchison J. Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review. JAMA.
2003;289:2992 - 9.

Hutchison JS, Ward RE, Lacroix J, Hebert PC, Barnes MA, Bohn DJ, et al. Hypothermia therapy after traumatic brain injury in children. N Engl J Med.
2008;358(23):2447-56.

Clifton GL, Valadka A, Zygun D, Coffey CS, Drever P, Fourwinds S, et al. Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial. Lancet Neurol. 2011;10(2):131-9.

Ghajar J. Traumatic brain injury. Lancet. 2000;356(9233):923-9.

Ducrocq S, Meyer P, Orliaguet G, Blanot S, Laurent-Vannier A, Renier D, et al. Epidemiology and early predictive factors of mortality and outcome in children with
traumatic severe brain injury: experience of a French pediatric trauma center. Pediatr Crit Care Med. 2006;7:461 - 7.

Wijayatilake DS, Shepherd SJ, Sherren PB. Updates in the management of intracranial pressure in traumatic brain injury. Curr Opin Anaesthesiol. 2012;25(5):540-7.

Sinclair HL, Andrews P. Bench-to-bedside review: Hypothermia in traumatic brain injury. Critical Care. 2010;14(1):204.

Lei J, Gao G, Mao Q, Feng J, Wang L, You W, et al. Rationale, methodology, and implementation of a nationwide multicenter randomized controlled trial of long-term mild hypothermia for severe traumatic brain injury (the LTH-1 trial). Contemporary clinical trials. 2015;40:9-14.

Andrews PJ, Sinclair HL, Rodriguez A, Harris BA, Battison CG, Rhodes JK, et al. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med. 2015;373(25):2403-12.

Ahmad FU, Starke RM, Komotar RJ, Connolly ES. A Randomized Clinical Trial of Hypothermia as a Preferred Second-Line Treatment for Elevated Intracranial Pressure After Traumatic Brain Injury. Neurosurgery. 2016;78(2):N10-1.

Zhu Y, Yin H, Zhang R, Ye X, Wei J. T h e r a p e u t i c h y p o t h e r m i a v e r s u s normothermia in adult patients with traumatic brain injury: a meta-analysis.
SpringerPlus. 2016;5(1):801.

Yokobori S, Yokota H. Targeted temperature management in traumatic brain injury. Journal of Intensive Care. 2016;4(1):28.

Rehman T, deBoisblanc BP. Persistent fever in the icu. CHEST Journal. 2014;145(1): 158-65.

Diringer MN, Reaven NL, Funk SE, Uman GC. Elevated body temperature independently contributes to increased length of stay in neurologic intensive care
unit patients*. Critical Care Medicine. 2004;32(7):1489-95.

Olsen TS, Weber UJ, Kammersgaard LP. Therapeutic hypothermia for acute stroke. Lancet Neurol. 2003;2(7):410-6.

Niven DJ, Laupland KB. Pyrexia: aetiology in the ICU. Critical Care. 2016;20(1):247.

Diringer MN, Group ftNCFRT. Treatment of fever in the neurologic intensive care unit with a catheter-based heat exchange system. Critical Care Medicine. 2004;32(2):559-64.

Mayer SA, Kowalski RG, Presciutti M, Ostapkovich ND, McGann E, Fitzsimmons B-F, et al. Clinical trial of a novel surface cooling system for fever control
in neurocritical care patients*. Critical care medicine. 2004;32(12):2508-15.

Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, et al. Fever control using external cooling in septic shock: a randomized controlled trial. Am J Respir Crit Care Med. 2012;185(10):1088-95.

Zhang Z. Antipyretic therapy in critically ill patients with established sepsis: a trial sequential analysis. PLoS One. 2015;10(2): e0117279.

Zhang Z, Chen L, Ni H. Antipyretic therapy in critically ill patients with sepsis: an interaction with body temperature. PLoS One. 2015;10(3):e0121919.

Bigelow WG, Callaghan JC, Hopps JA. General hypothermia for experimental intracardiac surgery; the use of electrophrenic respirations, an artificial pacemaker for cardiac standstill, and radio-frequency rewarming in general hypothermia. Transactions of the Meeting of the American Surgical Association American Surgical Association Meeting. 1950;68:211-9.

Bigelow WC. Methods for inducing hypothermia and rewarming. Ann N Y Acad Sci. 1959;80:522-32.

Todd MM, Hindman BJ, Clarke WR, Torner JC. Mild Intraoperative Hypothermia during Surgery for Intracranial Aneurysm. New England Journal of Medicine.
2005;352(2):135-45.

MacLellan CL, Girgis J, Colbourne F. Delayed onset of prolonged hypothermia improves outcome after intracerebral hemorrhage in rats. J Cereb Blood Flow
Metab. 2004;24(4):432-40.

Rincon F, Friedman DP, Bell R, Mayer SA, Bray PF. Targeted temperature management after intracerebral hemorrhage (TTM-ICH): methodology of a prospective randomized clinical trial. Int J Stroke. 2014;9(5):646-51.

Hansebout RR, Hansebout CR. Local cooling for traumatic spinal cord injury: outcomes in 20 patients and review of the literature: Clinical article. Journal of
Neurosurgery: Spine. 2014;20(5):550-61.

Neuberger J. Management of the Patient with Fulminant Hepatic Failure Awaiting Liver Transplantation. Liver Transplantation: John Wiley & Sons, Ltd; 2013. p. 93-100.

Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, et al. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function.
N Engl J Med. 2015;373(5):405-14.

Downloads

Published

2019-02-13

How to Cite

1.
Konmun S, Sriratanaporn S, Kitti-udom S, Muengtaweepongsa S. Targeted Temperature Management in Critical care Neurology. J Thai Stroke Soc [Internet]. 2019 Feb. 13 [cited 2024 Jun. 14];16(3):27-48. Available from: https://he01.tci-thaijo.org/index.php/jtss/article/view/172101

Issue

Section

Original article