Antiphospholipid syndrome presenting with acute stroke: case series and review of literature


  • กานน จตุวรพฤกษ์ คณะแพทยศาสตร์ โรงพยาบาลธรรมศาสตร์เฉลิมพระเกียรติ มหาวิทยาลัยธรรมศาสตร์


antiphospholipid syndrome, antiphospholipid antibodies, stroke, cerebrovascular disease


Antiphospholipid syndrome (APS) is an uncommon systemic autoimmune disease characterized by venous or arterial thrombosis and pregnancy complications in the context of persistent antiphospholipid antibodies. Clinical presentation of APS patients may vary depending on the organ systems affected. Recognition of APS among patients who present with acute stroke is difficult and often leads to delayed diagnosis or excessive investigations. Three patients who came to Thammasat University Hospital with acute stroke and were eventually diagnosed with APS are presented. The epidemiology, risk factors, clinical features, immunological profiles, radiographic findings, principle of diagnosis, along with treatment and outcomes of APS patients presenting with acute stroke are reviewed.


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How to Cite

จตุวรพฤกษ์ ก. Antiphospholipid syndrome presenting with acute stroke: case series and review of literature. J Thai Stroke Soc [Internet]. 2019 Feb. 13 [cited 2024 Jul. 21];16(1):5-15. Available from:



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