Prevalence and etiologies of ischemic stroke in young patients in Bhumibol Adulyadej Hospital

Authors

  • Sugipichcha Chantaraprapabkun Department of medicine, Bhumibol Adulyadej hospital, Directorate of Medical Services, Royal Thai Air Force
  • Saengduan Mayotarn Department of medicine, Bhumibol Adulyadej hospital, Directorate of Medical Services, Royal Thai Air Force
  • Supachat Chompoonuch Department of medicine, Bhumibol Adulyadej hospital, Directorate of Medical Services, Royal Thai Air Force
  • Sansanee Pongpakdee Department of medicine, Bhumibol Adulyadej hospital, Directorate of Medical Services, Royal Thai Air Force

Keywords:

Ischemic stroke, prevalence, etiology, young patient

Abstract

Objective: To study the prevalence and etiologies of ischemic stroke in young patients Materials and Methods: Medical records of ischemic stroke patients of age 15-45 years who were treated in Bhumibol Adulyadej Hospital from January 1, 2009 to December 31, 2013 were collected and reviewed. Results: Of 145 (5.37%) ischemic stroke patients in young adults included, 60.69% were male 100 aged 39.10+4.5 years and 39.31% were female aged 38.93+5.2 years. Common risk factors were smoking, alcohol drinking, hypertension, diabetes and dyslipidemia. According to Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification, types of stroke were stroke of undetermined etiology (47.6%), small-vessel occlusion (31%), cardioembolism (17.2%), large artery atherosclerosis (3.5%) and stroke of other determined etiology (0.7%). Conclusion: Prevalence of ischemic stroke in the young is 5.37% among all stroke patients. Stroke of undetermined etiology was the most common type according to TOAST classification. Further research in larger population with complete investigation is needed.

References

Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, et al. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013 Jul;44(7):2064-89.

Wasay M, Kaul S, Menon B, Venketasubramanian N, Gunaratne P, Khalifa A, et al. Ischemic stroke in young Asian women: risk factors, subtypes and outcome. Cerebrovascular diseases. 2010;30(4):418-22.

รัตนา นิลเพชร์พลอย, สมศักดิ์ เทียมเก่า, ทรงขวัญ ศิลารักษ์. โรคหลอดเลือดสมองชนิดขาดเลือดในผู้ป่วยอายุน้อยในโรงพยาบาลศรีนครินทร์. ศรีนครินทร์เวชสาร 2547;19(3):122-130.

Suwanwela NC. Stroke epidemiology in Thailand. Journal of stroke. 2014 Jan;16(1):1-7.

Chraa M, Louhab N, Kissani N. Stroke in young adults: about 128 cases. The Pan African medical journal. 2014;17:37.

Lee TH, Hsu WC, Chen CJ, Chen ST. Etiologic study of young ischemic stroke in Taiwan. Stroke. 2002 Aug;33(8):1950-5.

Amarenco P, Bogousslavsky J, Caplan LR, Donnan GA, Hennerici MG. Classification of stroke subtypes. Cerebrovascular diseases.
2009;27(5):493-501.

Martin PJ, Enevoldson TP, Humphrey PR. Causes of ischaemic stroke in the young. Postgraduate medical journal. 1997 Jan;73(855):8-16.

Ghandehari K, Moud ZI. Incidence and etiology of ischemic stroke in Persian young adults. Acta neurologica Scandinavica. 2006 Feb;113(2):121-4.

Li F, Yang L, Yang R, Xu W, Chen FP, Li N, et al. Ischemic Stroke in Young Adults of Northern China: Characteristics and Risk Factors for Recurrence. European neurology. 2017;77(3-4):115-22.

Kwon SU, Kim JS, Lee JH, Lee MC. Ischemic stroke in Korean young adults. Acta neurologica Scandinavica. 2000 Jan;101(1):19-24.

Khan FY. Risk factors of young ischemic stroke in Qatar. Clinical neurology and neurosurgery. 2007 Nov;109(9):770-3.

Awada A. Stroke in Saudi Arabian young adults: a study of 120 cases. Acta neurologica Scandinavica. 1994 May;89(5):323-8.

Putaala J, Metso TM, Metso AJ, Makela E, Haapaniemi E, Salonen O, et al. Thrombolysis in young adults with ischemic stroke. Stroke. 2009 Jun;40(6):2085-91.

Varona JF, Guerra JM, Bermejo F, Molina JA, Gomez de la Camara A. Causes of ischemic stroke in young adults, and evolution of the etiological diagnosis over the long term. European neurology. 2007;57(4):212-8.

Downloads

Published

2019-02-13

How to Cite

1.
Chantaraprapabkun S, Mayotarn S, Chompoonuch S, Pongpakdee S. Prevalence and etiologies of ischemic stroke in young patients in Bhumibol Adulyadej Hospital. J Thai Stroke Soc [Internet]. 2019 Feb. 13 [cited 2024 Jun. 22];17(3):5-14. Available from: https://he01.tci-thaijo.org/index.php/jtss/article/view/172072

Issue

Section

Original article