Cryptogenic stroke


  • สุภารัตน์ วินิจปรีชากุล คณะแพทยศาสตร์วชิรพยาบาล มหาวิทยาลัยนวมินทราธิราช


Cryptogenic stroke, ESUS (Embolic Stroke of Undetermined Source), occult atrial fibrillation, patent foramen ovale


Cryptogenic stroke can be found one quarter of all ischemic stroke patient. Most of cryptogenic stroke is caused by emboli in origin and defined as ESUS.Standard work up to define the cause of cryptogenic stroke should be including echocardiography, 24-hour cardiac monitoring, intracranial and extracranial vascular imaging and blood tests for hypercoagulable state.Most possible potential causes of cryptogenic stroke are occult AF, PFO and non-stenosis ulcerated atherosclerotic plaque.Currently, guideline treatment of cryptogenic stroke, including combination of antiplatelet medication and modified stroke risk factors. Long term cardiac monitoring can detect more atrial fibrillation (AF) which should be beneficial for anticoagulant therapy.However, further ongoing large RCT should give more data and will suggest how to manage in these patient groups.


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How to Cite

วินิจปรีชากุล ส. Cryptogenic stroke. J Thai Stroke Soc [Internet]. 2019 Feb. 13 [cited 2024 Jun. 14];17(1):19-31. Available from:



Original article