เทคนิคการฉายรังสีด้วยอนุภาคโปรตอนในโรคมะเร็งตับ โรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย

Tanapat  Tiajaroen; Phattarawadee Phromngulueam; Phatthraporn Thasasi

Authors

Tanapat Tiajaroen Division of Radiation Oncology, Department of Radiology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society
Phattarawadee Phromngulueam Division of Radiation Oncology, Department of Radiology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society
Phatthraporn Thasasi Division of Radiation Oncology, Department of Radiology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society

Abstract

Proton beam therapy is an effective and highly precise treatment option for liver cancer, owing to the unique physical properties of protons that allow maximal energy deposition at the tumor site while minimizing radiation exposure to surrounding normal tissues. This characteristic enables the delivery of high radiation doses for effective tumor control with a low incidence of treatment-related toxicity. However, proton therapy for liver cancer requires technically complex procedures, as the liver is a highly mobile organ and is located in close proximity to several critical structures. This article aims to present the technical approaches and clinical experience of proton beam therapy for liver cancer at King Chulalongkorn Memorial Hospital, Thai Red Cross Society. This article covers the entire treatment workflow, including simulation, patient positioning and selection of appropriate immobilization devices, respiratory motion management techniques, treatment planning, and image guidance. These components play a crucial role in reducing uncertainties, enhancing treatment accuracy, and minimizing radiation-induced toxicity to adjacent critical organs, such as the stomach, intestines, and kidneys.

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