การศึกษาเรื่องมะเร็งปากมดลูกระยะที่ IIB และ IIB ที่รักษา ด้วยการฉายรังสีร่วมกับยาเคมีบำบัด ในศูนย์ป้องกันและควบคุมโรคมะเร็ง จังหวัดลพบุรี ระหว่างเดือนสิงหาดม พ.ศ. 2542 ถึงเดือนกรกฎาคม พ.ศ. 2544
Abstract
Suity w rociona rito witite enis tue I till reed by ose ose Coplinging or Carboplatin and radiation therapy in the section of Radiation Oncology Lopburi Regional Cancer Centre between August 19999 and July 2001 revealed 16 patients with curative intent. Patients with stage IIB were 12 cases (75%), and stage IIIB were 4 cases (25%). Mean age was 45.4 years old, ranging from 34 to 53 years old. All of patients were started with external irradiation by 6 MV Linear Accelerator for 5-6 weeks followed by 1-2 times of MDR brachytherapy Cs-137 RALS. Cisplatin or Carboplatin was prescribed concurrently with external irradiation. The acute toxicities (hematologic and non-hematologic) were only grade I-II in both regimens (grade II hematologic and non-hematologic toxicity = 43.75% and 0% respectively). At 3 months after complete radiotherapy, 93.75% of patients had clinically complete response. The minimal follow up time was 11 months and the maximum was 33 months (median 20 months). Local failure rate was 12.5% (6.25% if excluded out-field failure case). Distant metastatic rate was 12.5%. 15 months disease free survival were equal in both stage IIB and IIIB patients (75%). Major complications (grade 2 or 3 side effects) were 18.75%. In conclusions, the patients in this study had good local control and survival with this regimen of concurrent chemoradiotherapy while only minimal toxicities were observed.
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บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของวารสารมะเร็งวิวัฒน์ ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับ และบุคคลากรท่านอื่น ๆ ใน สมาคมฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใดๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว
