Experiences in the treatment of Osteosarcoma in Ramathibodi Hospital
Abstract
One hundred thirty cases of osteosarcoma were enrolled to the multidisciplinary treatment. The 9 years survival probability was 55% and the survival was stable after 4.4 years. Local irradiation of the primary tumor was proved to increase chance of limb salvage surgery (p = 0.007) and provided more tumor response as compare to the control patients (p = 0.14). The 9 years survival in the patients with local radiation was 70% and dropped to 45% in the non radiation. (log-rank = 0.01). Prophylactic whole lung irradiation also beneficially decreased the incidence of lung metastases (p = 0.0009) and the 9 years survival was 70% versus 46% in PLI and non PLI patients (log-rank = 0.05).
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บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของวารสารมะเร็งวิวัฒน์ ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับ และบุคคลากรท่านอื่น ๆ ใน สมาคมฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใดๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว
