Present status of carcinoma of the uterine cervix and standardisation of its treatment in Thailand.

Abstract

In Thailand the most common female cancer was carcinoma of the uterine cervix. It's estimated national age-standardised incidence as 23.4 per 100,000. The peak age group was between 41-59 year old. The most important risk factors were among women with low socio-economic and who had been infected by HPV. The stage distributions of the disease were about 10-15%, 40-50%, 30-45%, , and 3-5-5% in stage I, II, III and IV, respectively. Nearly 90% of cases were sequamous cell carcinoma. Adenocarcinoma about 10% and others were about 2-3%. The treatment of stage I was surgery, while stage II-IV main modality was radiotherapy. Chemotherapy was preserved for measurable residual tumor, recurrence or in study protocols. The 5 yr. survival rate in stage I, II, III and IV were about 75-90%, 50-80%, 30-50%o and 0%, respectively. The most common acute effect was mild diarrhea. The common late effects cystitis and proctitis, but severe status was less than 5%. (Presented in The International Nuclear Co-operation in Asia Seminar at Kuala Lumper,5-11 December 1994.)