The Effect of Overall Treatment Time of Radiotherapy to Local Control of Disease in Head and Neck Cancer

Authors

  • Rungarun Kittichest Faculty of Medicine, Chiang Mai University
  • Imjai Chitapanarux Faculty of Medicine, Chiang Mai University
  • Vicharn Lorvidhaya Faculty of Medicine, Chiang Mai University
  • Pimkhuan Kamnerdsupaphon Faculty of Medicine, Chiang Mai University
  • Vimol Sukthomya Faculty of Medicine, Chiang Mai University

Abstract

Background : Radiotherapy is commonly used in the management of patients with squamous cell carcinoma of head and neck. Various studies showed the total treatment time effect tumor control.

Purpose : To evaluate the effect of prolonged overall treatment time to the tumor control in squamous cell carcinoma of head and neck.

Methods and materials : Data from 114 patients with histological confirmed squamous cell carcinoma of head and neck (excluded nasopharyngeal cancer) were treated with radiotherapy at Department of Radiation Oncology, Chiang mai University, since 2001 (2544) - 2003 (2546), attention in duration of response and overall survival.

Results : All 114 squamous cell carcinoma of head and neck patients were treated with radiotherapy differentiated into two groups by total treatment time, group A:6-8 weeks and group B: more than 8 weeks. Median overall treatment time was 55.8 days (range 42-88 days). Overall 4-years locoregional progression rate were 47.7% for group A and 60.7% for group B, respectively (p=0.3532). Four year overall survival was 98.7% for group A and 83.3% for group B (p=0.4310).

Conclusion : The prolongation of overall treatment time trends to have poorer outcome in locoregional control and overall survival.

References

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vol13No1

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Published

2007-12-28

How to Cite

1.
Kittichest R, Chitapanarux I, Lorvidhaya V, Kamnerdsupaphon P, Sukthomya V. The Effect of Overall Treatment Time of Radiotherapy to Local Control of Disease in Head and Neck Cancer. J Thai Assn of Radiat Oncol [Internet]. 2007 Dec. 28 [cited 2024 Dec. 21];13(2):37-45. Available from: https://he01.tci-thaijo.org/index.php/jtaro/article/view/203567

Issue

Vol. 13 No. 2 (2007): July – December

Section

Original articles

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