Survival in endometrial cancer

Authors

  • Nithinai Tangprasert Radiologic Oncologist, Radiation Therapy Unit, National Cancer Institute Thailand
  • Sukumarn Sanersak Swangvaree Gynecologic Oncologist, Gynecological Oncology Unit, National Cancer Institute Thailand

Keywords:

survival, endometrial cancer, radiotherapy

Abstract

Objective; To identifi ed survival of endometrial cancer patients in National Cancer Institute of Thailand. Material and Method ; This is a retrospective descriptive study. All patients with endometrial cancer who received treatment in National Cancer Institute From 1987-2004 were included. Results ; Five hundred and seventy nine patients with endometrial cancer that met the study criteria were included. The median age of the patients were 54.13 years. The median overall survival was 93.75 months. The 5 year survival of endometrial cancer patients were 84.1% in stage I, 63.6 % in stage II, 53.5% in stage III, and 13.6% in stage IV. In patient, were received radiotherapy, had overall survival about 70.1% at 5 years. In cases of intermediated to high risk of recurrence endometrial cancer had no statistically signifi cant in difference of overall survival between radiation and non-radiation group. Conclusion ; The survival in endometrial cancer patients were good and radiation in intermediate to high risk of recurrence was not increase overall survival.

References

American College of Obstetricians and Gynecologists, In: DiSaia PJ, ed Precis V : An update in obstetrics and gynecology , Washington DC : ACOG, 1994: 326-7.

Creasman WT, Soper JT. Assessment of the contemporary management of germ cell malignancies of the ovary. Am J Obstet Gynecol 1985;153: 828-34.

Khuhaprema T, Srivatanakul P, Sriplung H, et al, editor. Cancer in Thailand: corpus uteri. Bangkok Medical Publisher 2007: 54-55.

Creasman WT, Odicino F, Maisonneuve P et al. Carcinoma of the corpus uteri. Int J Gynaecol Obstet 2003;83(Supp. 11):79–118.

American Cancer Society. Cancer facts & fi gures 2006. Available at http://www.cancer.org/docroot/STT/stt_0.asp. Accessed August 1, 2006.

David T. Shaefer, Marcus E. Randall. Adjuvant Radiotherapy in Endometrial Carcinoma. The Oncologist 2005;10:623-31.

Aalders J, Abeler V, Kolstad P, Onsrud M. Postoperative external irradiation and prognostic parameters in stage I endometrial carcinoma. Obstet Gynecol 1980;56:419–27.

Creutzberg CL, van Putten WL, Koper PC et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 2000;355: 1404–11.

Scholten AN, van Putten WL, Beerman H et al. Postoperative radiotherapy for stage 1 endometrial carcinoma: long-term outcome of the randomized PORTEC trial with central pathology review. Int J Radiat Oncol Biol Phys 2005;63:834–8.

Keys HM, Roberts JA, Brunetto VL et al. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 2004;92:744–51.

Stewart KD, Martinez AA, Weiner S, et al. Ten-year outcome including patterns of failure and toxicity for adjuvant whole abdominopelvic irradiation in high-risk and poor histologic feature patients with endometrial carcinoma. Int J Radiat Oncol Biol Phys 2002;54:527-35.

Martinez A, Podratz K: Results of whole adomino-pelvic radiation with nodal boost for patients with endometrial cancer at high risk of failure in the peritoneal cavity. Hematol Oncol Clin North Am 1998;2:431.

Angeles Alvarez Secord, Laura J. Havrilesky, Victoria Bae-Jump et al. The role of multi-modality adjuvant chemotherapy and radiation in women with advanced stage endometrial cancer. Gyn Oncol 2007;107:285-91.

Creasman WT, Odicino F, Maisonneuve P, Quinn MA, Beller U, Benedet JL, et al. Carcinoma of the corpus uteri. FIGO 6th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 2006;95:S105-43.

Santin AD, Bellone S, Brien TJ, et al. Current Treatment options for endometrial cancer. Expert Rev Anticancer 2004;4:679-89.

Johnson N, Cornes P. Survival and recurrent disease after postoperative radiotherapy for early endometrial cancer : systematic review and meta-analysis. BJOG 2007;114:1313-20.

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Published

2010-06-29

How to Cite

1.
Tangprasert N, Swangvaree SS. Survival in endometrial cancer. J Thai Assn of Radiat Oncol [Internet]. 2010 Jun. 29 [cited 2024 Jul. 3];16(1):21-6. Available from: https://he01.tci-thaijo.org/index.php/jtaro/article/view/203512

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Original articles