Human Papilloma Virus in Oropharyngeal Carcinoma

Authors

  • Pittaya Dankulchai Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Kullathorn Thephamongkhol Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Thong Narawiwat Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Yaowalak Chansilpa Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University

Abstract

Oropharyngeal cancer, the second most common of head and neck cancer patients in Siriraj hospital, is a challenging disease in head and neck squamous cell carcinoma (HNSCC). Although tobacco use is known the predominant risk factor in oropharyngeal oncogenesis. A very interesting etiological linkage between the human papillomavirus (HPV) and a subgroup of HNSCC has recently been established. At this time, in the year of 2011, we have more and more scientifi c data to support that tumor HPV status is a paramount prognostic biomarker for head and neck cancers in terms of tumor control, disease free survival and overall survival. In other words, the group of HPV positive patients has defi nitely better prognosis. In the near future, results from clinical trials on oropharyngeal cancer will inform us the better way how to treat these groups of patients without any compromise in survival and less toxicity.

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Published

2011-06-29

How to Cite

1.
Dankulchai P, Thephamongkhol K, Narawiwat T, Chansilpa Y. Human Papilloma Virus in Oropharyngeal Carcinoma. J Thai Assn of Radiat Oncol [Internet]. 2011 Jun. 29 [cited 2024 Nov. 15];17(1):92-8. Available from: https://he01.tci-thaijo.org/index.php/jtaro/article/view/203492

Issue

Vol. 17 No. 1 (2011): January - June

Section

Review articles

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