The difference of High-risk Clinical Target Volumes (HR-CTV) between Computed Tomography and Magnetic Resonance Imaging in Cervical Cancer.

Authors

  • Ekkasit Tharavichitkul Faculty of Medicine, Chiang Mai University
  • Nattawoot Samorn Faculty of Medicine, Chiang Mai University
  • Roongtip jaiyaswasdi Faculty of Medicine, Chiang Mai University
  • Somsak Wanwilairat Faculty of Medicine, Chiang Mai University
  • Sanchai Lookaew Faculty of Medicine, Chiang Mai University
  • Wannapa Nopnop Faculty of Medicine, Chiang Mai University
  • Juljira Wannasri Faculty of Medicine, Chiang Mai University
  • Imjai Chitapanarux Faculty of Medicine, Chiang Mai University

Keywords:

cervix cancer, brachytherapy, target volume comparison

Abstract

Purpose: This study was carried out to evaluate the volume and dose of HR-CTV between CT and MRI in intracavitary brachytherapy of cervical cancer. Materials and methods: Retrospective data from the MRI and CT imaging of the fi rst application of fi fteen patients with locally advanced carcinoma of cervix uteri were collected and evaluated in terms of volume-based concepts. The volume and D90 of HR-CTV of MRI was compared with the HR-CTV of CT with the concepts of the Groupe Européen de Curiethérapie - European Society for Therapeutic Radiology and Oncology (GEC-ESTRO). Results: No statistical signifi cance between the MRI and CT of HR-CTV was observed. Conclusion: The volumes of HR-CTV of MRI versus CT were not statistically signifi cant although the MRI yielded good tumor identifi cation.

References

International Commission on Radiation Units and Measurements. ICRU report 38: Dose and volume specifi cation for reporting intracavitary therapy in gynecology. Bethesda: International Commission on Radiation Units and Measurements. 1985

Hricak H, Lacey CG, Sandles LG, Chang YC, Winkler ML and SternJL. Invasive cervical carcinoma: comparison of MR imaging and surgical fi ndings. Radilogy 1988; 166: 623-631.

Togashi K, Nishimura K, Sagoh T, Minami S, Noma S, Fujisawa I, Nakano Y, Konishi J, Ozasa H, Konishi I, et al.Carcinoma of cervix: staging with MR imaging. Radiology 1989; 171(1): 245-251.

Mell LK, Kochanski JD, Roeske JC, Haslam JJ, Mehta N, Yamada SD, Hurteau JA, Collins YC, Lengyel E, Mundt AJ. Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy. Int J Radiat Oncol Biol Phys 2006; 66(5): 1356–1365.

Portelance L, Chao KS, Grigsby PW, Bennet H, Low D.Intensity-modulated radiation therapy (IMRT) reduces small bowel, rectum, and bladder doses in patients with cervical cancer receiving pelvic and para-aortic irradiation. Int J Radiat Oncol Biol Phys 2001; 51(1):
261–266.

Van de Bunt L, van der Heide UA, Ketelaars M, de Kort GA, Jürgenliemk-Schulz IM.Conventional, conformal, and intensity-modulated radiation therapy treatment planning of external beam radiotherapy for cervical cancer: The impact of tumor regression. Int J Radiat Oncol Biol Phys 2006; 64(1): 189–196.

Salama JK, Mundt AJ, Roeske J, Mehta N.Preliminary outcome and toxicity report of extended-fi eld, intensity-modulated radiation therapy for gynecologic malignancies. Int J Radiat Oncol Biol Phys 2006; 65(4): 1170–1176

Haie-Meder C, Pötter R, Van Limbergen E, Briot E, De Brabandere M, Dimopoulos J, Dumas I, Hellebust TP, Kirisits C, Lang S, Muschitz S, Nevinson J, Nulens A, Petrow P, Wachter-Gerstner N; Gynaecological (GYN) GEC-ESTRO Working Group.Recommendations
from Gynecological (GYN) GEC-ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 2005; 74 (3): 235–245.

Pötter R, Haie-Meder C, Van Limbergen E, Barillot I, De Brabandere M, Dimopoulos J, Dumas I, Erickson B, Lang S, Nulens A, Petrow P, Rownd J, Kirisits C; GEC ESTRO Working Group. Recommendations from gynecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 2006; 78(1): 67–77.

Pötter R, Dimopoulos J, Georg P, Lang S, Waldhäusl C, Wachter-Gerstner N, Weitmann H, Reinthaller A, Knocke TH, Wachter S, Kirisits C. Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol 2007; 83(2):148–155.

Viswanathan AN, Dimopoulos J, Kirisits C, Berger D, Pötter R. Computed tomography versus magnetic resonance image-based contouring in cervical cancer brachytherapy : Result of a prospective trial and preliminary guidelines for standard contours. Int J Radiat Oncol Biol Phys 2007; 68(2):491–498.

Eskander RN, Scanderbeg D, Saenz CC, Brown M, Yashar C.Comparison of computed tomography and magnetic resonance imaging in cervical cancer brachytherapy target and normal tissue contouring. Int J Gynecol cancer 2010; 20(1): 47-53.

Downloads

Published

2012-06-29

How to Cite

1.
Tharavichitkul E, Samorn N, jaiyaswasdi R, Wanwilairat S, Lookaew S, Nopnop W, Wannasri J, Chitapanarux I. The difference of High-risk Clinical Target Volumes (HR-CTV) between Computed Tomography and Magnetic Resonance Imaging in Cervical Cancer. J Thai Assn of Radiat Oncol [Internet]. 2012 Jun. 29 [cited 2024 Dec. 21];18(1):43-6. Available from: https://he01.tci-thaijo.org/index.php/jtaro/article/view/203465

Issue

Section

Original articles