Enhanced recovery after abdominal surgery in pediatric patients

Authors

  • Nutthavit Hantanyapong Pediatric Surgery Unit, Division of Surgery, Nakhon Pathom Hospital

Keywords:

enhanced recovery after surgery, perioperative management, abdominal surgery, pediatric patient

Abstract

Enhanced Recovery After Surgery (ERAS) guidelines for pediatric patients have been developed over the past decade to reduce the stress responses associated with surgical procedures, preserve organ function, and promote early recovery. Key components of ERAS in pediatric surgery emphasize a multidisciplinary approach, requiring collaboration among pediatric surgeons, pediatricians, anesthesiologists, and nursing staff during the perioperative period. Preoperative management focuses on educating patients and guardians about the surgical procedure and the ERAS protocol, ensuring optimal medical conditions, and establishing appropriate fasting requirements. Intraoperative strategies prioritize minimally invasive techniques over exploratory laparotomy, while avoiding the use of abdominal drains and nasogastric tubes. Other essential practices include proper antibiotic prophylaxis, judicious fluid management, patient normothermia, prophylaxis for nausea and vomiting, and multimodal pain control. Postoperatively, protocols advocate for early ambulation, prompt initiation of enteral feeding, early removal of nasogastric tubes and Foley catheters, and avoidance of intravenous opioids, favoring multimodal pain management instead. The implementation of ERAS protocols in pediatric surgery offers significant benefits for patients, families, and healthcare providers by promoting early mobilization and encouraging parental involvement. ERAS enhances recovery, reduces the incidence of complications, and shortens the length of hospital stay. Additionally, ERAS in pediatrics has shown potential to lower healthcare costs, optimize resource utilization, and improve long-term outcomes for children undergoing surgery. This article presents data on the ERAS protocol for pediatric patients undergoing abdominal surgery, highlighting its advantages, management strategies, and significance in improving preoperative, perioperative, and postoperative care to promote early recovery in pediatric abdominal surgery.

References

Fearon KC, Ljungqvist O, Von Meyenfeldt M, et al. Enhanced recovery after surgery: A consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 2005;24:466-77. doi:10.1016/j.clnu.2005.02.002.

Dean HF, Carter F, Francis NK. Modern perioperative medicine - past, present, and future. Innov Surg Sci 2019;4:123-31. doi:10.1515/iss-2019-0014.

Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for perioperative care in elective colorectal surgery: Enhanced recovery after surgery (ERAS®) society recommendations: 2018. World J Surg 2019;43:659-95. doi:10.1007/s00268-018-4844-y.

Joliat GR, Kobayashi K, Hasegawa K, et al. Guidelines for perioperative care for liver surgery: Enhanced recovery after surgery (ERAS) society recommendations 2022. World J Surg 2023;47:11-34. doi:10.1007/s00268-022-06732-5.

Wainwright TW, Gill M, McDonald DA, et al. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Acta Orthop 2020;91:3-19. doi:10.1080/17453674.2019.1683790.

Debono B, Wainwright TW, Wang MY, et al. Consensus statement for perioperative care in lumbar spinal fusion: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Spine J 2021;21:729-52. doi:10.1016/j.spinee.2021.01.001.

Su Y, Xu L, Hu J, et al. Meta-Analysis of Enhanced Recovery After Surgery Protocols for the Perioperative Management of Pediatric Colorectal Surgery. J Pediatr Surg 2023;58:1686-93. doi:10.1016/j.jpedsurg.2022.11.017.

Perez MN, Raval MV. Evolution of enhanced recovery for children undergoing elective intestinal surgery. Semin Pediatr Surg 2024;33:151400. doi:10.1016/j.sempedsurg.2024.151400.

Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery: A review. JAMA Surg 2017;152:292-8. doi:10.1001/jamasurg.2016.4952.

Roberts K, Brindle M, McLuckie D. Enhanced recovery after surgery in paediatrics: A review of the literature. BJA Educ 2020;20:235-41. doi:10.1016/j.bjae.2020.03.004.

Arena S, Di Fabrizio D, Impellizzeri P, et al. Enhanced recovery after gastrointestinal surgery (ERAS) in pediatric patients: A systematic review and meta-analysis. J Gastrointest Surg 2021;25:2976-88. doi:10.1007/s11605-021-05053-7.

Hidayah BA, Toh ZA, Cheng LJ, et al. Enhanced recovery after surgery in children undergoing abdominal surgery: Meta-analysis. BJS Open 2023;7:zrac147. doi:10.1093/bjsopen/zrac147.

Jimenez-Arribas P, Nunez Garcia B. ERAS(R) in pediatric surgery: Is it time for a change? Cir Pediatr 2021;34:111-2.

Lau CS, Chamberlain RS. Enhanced recovery after surgery programs improve patient outcomes and recovery: A meta-analysis. World J Surg 2017;41:899-913. doi:10.1007/s00268-016-3807-4.

Uday Bhaskar MNS, Sundararajan L. Feasibility of enhanced recovery after aurgery in pediatric colostomy reversal. J Indian Assoc Pediatr Surg 2023;28:319-24. doi:10.4103/jiaps.jiaps_107_22.

Puett LL, Smith L. Feasibility of enhanced recovery protocols in children. J Pediatr Surg Nurs 2018;7:9-19. doi:10.1097/JPS.0000000000000159.

Di Sarno L, Gatto A, Korn D, et al. Pain management in pediatric age. An update. Acta Biomed 2023;94:e2023174. doi:10.23750/abm.v94i4.14289.

Sansone L, Gentile C, Grasso EA, et al. Pain evaluation and treatment in children: A practical approach. Children (Basel) 2023;10:1212. doi:10.3390/children10071212.

Willis MA, Toews I, Soltau SL, et al. Preoperative combined mechanical and oral antibiotic bowel preparation for preventing complications in elective colorectal surgery. Cochrane Database Syst Rev 2023;2:CD014909. doi:10.1002/14651858.CD014909.

Janssen Lok M, Miyake H, O’Connell JS, et al. The value of mechanical bowel preparation prior to pediatric colorectal surgery: A systematic review and meta-analysis. Pediatr Surg Int 2018;34:1305-20. doi:10.1007/s00383-018-4345-y.

Chen M, Lin J, Miao D, et al. The effect of preoperative mechanical bowel preparation in paediatric bowel surgery on postoperative wound related complications: A meta-analysis. Int Wound J 2024;21:e14884. doi:10.1111/iwj.14884.

Dagorno C, Montalva L, Ali L, et al. Enhancing recovery after minimally invasive surgery in children: A systematic review of the literature and meta-analysis. J Pediatr Surg 2021;56:2157-64. doi:10.1016/j.jpedsurg.2021.04.004.

Joshi GP, Abdelmalak BB, Weigel WA, et al. 2023 American Society of Anesthesiologists practice guidelines for preoperative fasting: Carbohydrate-containing clear liquids with or without protein, chewing gum, and pediatric fasting duration-A modular update of the 2017 American Society of Anesthesiologists practice guidelines for preoperative fasting. Anesthesiology 2023;138:132-51. doi:10.1097/ALN.0000000000004381.

Rove KO, Edney JC, Brockel MA. Enhanced recovery after surgery in children: Promising, evidence-based multidisciplinary care. Paediatr Anaesth 2018;28:482-92. doi:10.1111/pan.13380.

Global Initiative for Children’s Surgery. Global Initiative for Children’s Surgery: A model of global collaboration to advance the surgical care of children. World J Surg 2019;43:1416-25. doi:10.1007/s00268-018-04887-8.

Kiblawi R, Zoeller C, Zanini A, et al. Laparoscopic versus open pediatric surgery: Three decades of comparative studies. Eur J Pediatr Surg 2022;32:9-25. doi:10.1055/ s-0041-1739418.

User IR, Ardicli B, Ciftci AO, et al. Early postoperative complications in pediatric abdominal solid tumor surgery according to Clavian-Dindo classification. Pediatr Surg Int 2022;38:1303-10. doi:10.1007/s00383-022-05163-6.

Feng C, Sidhwa F, Cameron DB, et al. Rates and burden of surgical site infections associated with pediatric colorectal surgery: Insight from the National Surgery Quality Improvement Program. J Pediatr Surg 2016;51:970-4. doi:10.1016/j.jpedsurg.2016.02.063.

Tobias J, Padilla BE, Lee J, et al. Standardized perioperative care reduces colorectal surgical site infection in children: A Western Pediatric Surgery Research Consortium multicenter analysis. J Pediatr Surg 2023;58:45-51. doi:10.1016/j.jpedsurg.2022.09.026.

Pough K, Bhakta R, Maples H, et al. Evaluation of pediatric surgical site infections associated with colorectal surgeries at an academic children’s hospital. Healthcare (Basel) 2020;8:91. doi:10.3390/healthcare8020091.

Nemeth M, Miller C, Bräuer A. Perioperative hypothermia in children. Int J Environ Res Public Health 2021;18:7541. doi:10.3390/ijerph18147541.

Shinnick JK, Short HL, Heiss KF, et al. Enhancing recovery in pediatric surgery: A review of the literature. J Surg Res 2016;202:165-76. doi:10.1016/j.jss.2015.12.051.

Mathew A, Rai E. Pediatric perioperative fluid management. Saudi J Anaesth 2021;15:435-40. doi:10.4103/sja.sja_140_21.

Edney JC, Lam H, Raval MV, et al. Implementation of an enhanced recovery program in pediatric laparoscopic colorectal patients does not worsen analgesia despite reduced perioperative opioids: A retrospective, matched, non-inferiority study. Reg Anesth Pain Med 2019;44:123-9. doi:10.1136/rapm-2018-000017.

Short HL, Heiss KF, Burch K, et al. Implementation of an enhanced recovery protocol in pediatric colorectal surgery. J Pediatr Surg 2018;53:688-92. doi:10.1016/j.jpedsurg.2017.05.004.

Vrecenak JD, Mattei P. Fast-track management is safe and effective after bowel resection in children with Crohn’s disease. J Pediatr Surg 2014;49:99-102; discussion 102-3. doi:10.1016/j.jpedsurg.2013.09.038.

Frizzell KH, Cavanaugh PK, Herman MJ. Pediatric perioperative pain management. Orthop Clin North Am 2017;48:467-80. doi:10.1016/j.ocl.2017.06.007.

Hong JY, Kim WO, Koo BN, et al. Fentanylsparing effect of acetaminophen as a mixture of fentanyl in intravenous parent-/nurse-controlled analgesia after pediatric ureteroneocystostomy. Anesthesiology 2010;113:672-7. doi:10.1097/ALN.0b013e3181e2c34b.

Nelson R, Edwards S, Tse B. Prophylactic nasogastric decompression after abdominal surgery. Cochrane Database Syst Rev 2007;2007:CD004929. doi:10.1002/14651858.CD004929.pub3.

Tazreean R, Nelson G, Twomey R. Early mobilization in enhanced recovery after surgery pathways: Current evidence and recent advancements. J Comp Eff Res 2022;11:121-9. doi:10.2217/cer-2021-0258.

Tian Y, Zhu H, Gulack BC, et al. Early enteral feeding after intestinal anastomosis in children: A systematic review and meta-analysis of randomized controlled trials. Pediatr Surg Int 2021;37:403-10. doi:10.1007/s00383-020-04830-w.

Eeftinck Schattenkerk LD, Musters GD, de Jonge WJ, et al. Should primary anastomosis be considered more? A retrospective analysis of anastomotic complications in young children. World J Pediatr Surg 2023;6:e000565. doi:10.1136/wjps-2023-000565.

Mattioli G, Palomba L, Avanzini S, et al. Fast-track surgery of the colon in children. J Laparoendosc Adv Surg Tech A 2009;19:S7-9. doi:10.1089/lap.2008.0121.supp.

Frischer JS, Rymeski B. Complications in colorectal surgery. Semin Pediatr Surg 2016;25:380-7. doi:10.1053/j.sempedsurg.2016.10.008.

Grisotti G, Cowles RA. Complications in pediatric hepatobiliary surgery. Semin Pediatr Surg 2016;25:388-94. doi:10.1053/j.sempedsurg.2016.10.004.

Pilkington M, Pentz B, Lam JY, et al. Bringing enhanced recovery after surgery to the NICU: An implementation trial. J Pediatr Surg 2024;59:557-65. doi:10.1016/j.jpedsurg.2023.11.025.

Brindle ME, McDiarmid C, Short K, et al. Consensus guidelines for perioperative care in neonatal intestinal surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 2020;44:2482-92. doi:10.1007/s00268-020-05530-1.

Gibb ACN, Crosby MA, McDiarmid C, et al. Creation of an Enhanced Recovery After Surgery (ERAS) Guideline for neonatal intestinal surgery patients: a knowledge synthesis and consensus generation approach and protocol study. BMJ Open 2018;8:e023651. doi:10.1136/bmjopen-2018-023651.

Ahn JJ, Martin LD, Low DK, et al. Enhanced recovery program in ambulatory pediatric urology: A quality improvement initiative. J Pediatr Urol 2024;20:744.e1-744.e7. doi:10.1016/j.jpurol.2024.04.015.

Melhem AM, Ramly EP, Al Abyad OS, et al. Enhanced recovery after cleft lip repair: Protocol development and implementation in Outreach settings. Cleft Palate Craniofac J 2023;60:724-33. doi:10.1177/10556656221078744.

Zhang H, Liu H, Zhang X, et al. Short-term outcomes of an enhanced recovery after surgery pathway for children with congenital scoliosis undergoing posterior spinal fusion: A case-control study of 70 patients. J Pediatr Orthop B 2024;33:258-64. doi:10.1097/BPB.0000000000001105.

Pennington Z, Cottrill E, Lubelski D, et al. Clinical utility of enhanced recovery after surgery pathways in pediatric spinal deformity surgery: Systematic review of the literature. J Neurosurg Pediatr 2020;27:225-38. doi:10.3171/2020.7.PEDS20444.

Svetanoff WJ, Diefenbach K, Hall B, et al. Utilization of an Enhanced Recovery After Surgery (ERAS) protocol for pediatric metabolic and bariatric surgery. J Pediatr Surg 2023;58:695-701. doi:10.1016/j.jpedsurg.2022.12.014.

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Published

2024-12-31

How to Cite

1.
Hantanyapong N. Enhanced recovery after abdominal surgery in pediatric patients. J Med Health Sci [Internet]. 2024 Dec. 31 [cited 2025 Jan. 9];31(3):136-51. Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/272685

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Review article (บทความวิชาการ)