Prognostic factors for 28-day survival following treatment in individuals with septic shock
Keywords:
septic shock, shock, survival, treatment process, vasopressorsAbstract
Septic shock is a condition commonly encountered in emergency rooms, and the survival of patients in this state depends on various factors, including both patient-related factors and emergency room treatment processes. From the research study, data were collected from November 1, 2022, to July 31, 2023, focusing on patients with septic shock who were aged 18 years or older and received treatment in the emergency department. A total of 111 individuals were included, comprising 68 survivors and 43 non-survivors. The data were analyzed using univariable logistic regression to identify factors influencing the 28-day survival outcome. It was found that age under 60 years OR=3.17 (95% CI=1.09-9.22, p-value 0.034), lower weight OR=0.96 (95% CI=0.92-0.99, p-value 0.036), lower initial NEWS score OR=0.88 (95% CI=0.79-0.99, p-value 0.028), and lower initial lactate level OR=0.90 (95% CI=0.81-0.99, p-value 0.028), as well as not requiring mechanical ventilation OR=0.29 (95% CI=0.13-0.65, p-value 0.003) and not receiving central venous catheterization for vasopressor administration OR=0.28 (95% CI=0.10-0.73, p-value 0.010), were statistically significant predictors of survival. These factors could be utilized for prognosticating 28-day survival significantly. However, when analyzed using multivariable logistic regression, only the factor of not requiring central venous catheterization for vasopressor administration remained statistically significant adjusted odds ratio 0.24 (95% CI=0.07-0.87, p-value = 0.029). Therefore, it can be concluded that patients who do not require central venous catheterization for vasopressor administration have a better prognosis compared to the other group.
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