Diagnostic accuracy of fine needle aspiration in thyroid mass in HRH Princess Maha Chakri Sirindhorn Medical Center
Keywords:
diagnostic accuracy of fine needle aspiration, fine needle aspiration, thyroid mass, thyroid cancerAbstract
Abstract
Fine needle aspiration (FNA) plays an important role in the diagnosis of thyroid mass because of its convenience, affordability, and ability to discriminate between benign and malignant thyroid mass. However, the predictive value of cancer by FNA cytological reports may vary compared to surgical pathology reports, which is the gold standard for diagnosis. Therefore, our research aims to measure the validity and efficacy of FNA cytological reports in comparison to the surgical pathology reports. A cross-sectional descriptive study comparing FNA cytological reports and surgical pathology reports in patients with thyroid mass was conducted at the department of Otolaryngology, HRH Princess Maha Chakri Sirindhorn Medical center (MSMC) from 1 January 2010 to 31 December 2019. The accuracy and efficacy of FNA for predicting thyroid cancer has been evaluated in this study. The total number of 234 patients with cytological reports from FNA who underwent surgical excision were included. This group constituted the basis of this study. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 64.8 (95% CI 50.6 - 76.9), 93.2 (95% CI 87.1 - 96.6), 79.5 (95% CI 64.2 - 89.7), 86.6 (95% CI 79.7 - 91.6) and 84.9 (95% CI 78.9 - 89.6) respectively. In conclusion, the results of this study showed that the FNA cytological reports from the Otolaryngologic department, MSMC can be used to help distinguish thyroid cancer from other thyroid mass. The validity and efficacy of FNA cytological reports were comparable to other studies. Our study confirmed that FNA is suitable for being used as a diagnostic test in patients with thyroid mass.
References
2. Roengkamol S. Fine needle aspiration of thyroid nodules at Surin Hospital. J of Srisaket Surin Buriram Hospital 2008;
23:357-69.
3. Mary EK, Paul EW, Cathleen MC, et al. The Washington manual of surgery. 8th edition. Philadelphia: WoltersKluwer; 2016.
4. Pauci AS, Braunwald E, Kaeper DI, et al. editors. Harrison’s principle of internal medicine. 20th edition. New York McGraw hill; 2015.
5. Rattanaarun K. Comparison of palpationguided versus ultrasound-guided fine needle aspiration biopsies in evaluation of nodular thyroid disease [Internet].
Songkhla: Faculty of medicine Songkla university; 2009. Available from http://www.rcot.org/download/resident_10_03.pdf.
6. Sudla J, Manotham P, Keansar L. Ultrasound guide thyroid with fine needle aspiration, FNA. J Siriraj Radiol 2015;1:30-7.
7. Cibase ES, Ali SZ. The 2017 Bethesda System for Reporting Thyroid Cytopathology. Thyroid 2017;27:1341-6.
8. Ali SZ, Cibas ES. The Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol 2009;132:658-65.
9. Karim MI, Nachev R, Fuklev N, et al. A study on evaluation of solitary nodular thyroid lesions by FNAC and its histopathological correlation. Bangladesh
J Med Sci 2019;18:789-95.
10. Buranachapkajorn P, Wattanachanya L, Boonchaya-anant P, et al. Endocrinology and Metabolism. Bangkok: Text and journal publication company limited; 2019.
11. Sharma C. Diagnostic accuracy of fine needle aspiration cytology of thyroid and evaluation of discordant cases. J Egypt Natl Cancer Inst 2015;27:147-53.
12. Ezza N, Sinna E.A. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions. J Egypt Natl Canc Instit 2012;24: 63-70.
13. Cap J, Ryska A, Rehorkova P, et al. Sensitivity and specificity of the fine needle aspiration biopsy of the thyroid: clinical point of view. Clin Endocrinol
1999;51:509.
14. Basharat R, Bukhari MH, Saeed S, et al.Comparison of fine needle aspiration cytology and thyroid scan in solitary thyroid nodule. Pathol Research Int 2011;2011.
15. Sinna E, Ezzat N. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions. J Egypt Natl Cancer Inst 2012;24: 63-70.
16. Rammeh S, Romdhane E, Sassi A, et al. Accuracy of fine-needle aspiration cytology of head and neck masses. Diagn Cytopathol 2019;
17. Thunyasiripong S. Accuracy of fine needle aspiration cytology in neck mass in Ranong hospital. Med J 2017;31:709-20.
18. Agarwal M, Sinha A, Agrawal C, et al. A comparative study of free-hand fine needle aspiration cytology and ultrasound guided fine needle aspiration cytology in the diagnosis of thyroid swellings at BP Koirala Institute of Health Sciences-a tertiary care centre in Nepal. Health Renaiss 2014;12:78-86.
19. Krishnappa P, Ramakrishnappa S, Kulkarni MH. Comparison of free hand versus ultrasound-guided fine needle aspiration of thyroid with histopathological correlation. J Environ Pathol Toxicol Oncol 2013;32(2).
