Diagnostic accuracy of fine needle aspiration in thyroid mass in HRH Princess Maha Chakri Sirindhorn Medical Center

Authors

  • Panuwat Wongwattana
  • Thitaporn Siangsung
  • Nareenart Bhuripongrat
  • Rattanan Pakornlersiri
  • Pichaporn Sataponpongpinyo
  • Romteera Chiencharoenthanakij
  • Atichaya Pongprasobchai

Keywords:

diagnostic accuracy of fine needle aspiration, fine needle aspiration, thyroid mass, thyroid cancer

Abstract

Abstract
Fine needle aspiration (FNA) plays an important role in the diagnosis of thyroid mass because of its convenience, affordability, and ability to discriminate between benign and malignant thyroid mass. However, the predictive value of cancer by FNA cytological reports may vary compared to surgical pathology reports, which is the gold standard for diagnosis. Therefore, our research aims to measure the validity and efficacy of FNA cytological reports in comparison to the surgical pathology reports. A cross-sectional descriptive study comparing FNA cytological reports and surgical pathology reports in patients with thyroid mass was conducted at the department of Otolaryngology, HRH Princess Maha Chakri Sirindhorn Medical center (MSMC) from 1 January 2010 to 31 December 2019. The accuracy and efficacy of FNA for predicting thyroid cancer has been evaluated in this study. The total number of 234 patients with cytological reports from FNA who underwent surgical excision were included. This group constituted the basis of this study. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 64.8 (95% CI 50.6 - 76.9), 93.2 (95% CI 87.1 - 96.6), 79.5 (95% CI 64.2 - 89.7), 86.6 (95% CI 79.7 - 91.6) and 84.9 (95% CI 78.9 - 89.6) respectively. In conclusion, the results of this study showed that the FNA cytological reports from the Otolaryngologic department, MSMC can be used to help distinguish thyroid cancer from other thyroid mass. The validity and efficacy of FNA cytological reports were comparable to other studies. Our study confirmed that FNA is suitable for being used as a diagnostic test in patients with thyroid mass.

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Published

2020-12-30

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Original Article (บทความวิจัย)