Preliminary study of neuroimaging and psychophysiology in adults with ADHD

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Ni Chun Hung
Shin-Hsien Lin
Mei Hung Chi
Po See Chen
I Hui Lee
Kao Chin Chen
Yen Kuang Yang


Attention Deficit Hyperactivity Disorder  (ADHD) affects in both children and adults leading
to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and psychophysiology outcomes in the adults with ADHD. Participants in this study consisted of three groups: unaffected fathers of offspring with ADHD, adults with ADHD, and matched controls, were enrolled. A psychological battery was used in order to assess the participants’ cool cognitive function. Levels of dopaminergic activity were assessed by using the single positron emission computed tomography (SPECT) with [99mTc] TRODAT-1. In a pilot test for further study, the Iowa gambling
test in a mock functional MRI was conducted. Molecular neuroimaging indicated the pivotal
role of dopaminergicactivity altered a swellas functional brain imaging demonstrated difference between cool and hot executive functions. Using the Event-Related Potentials (ERP), the P300 amplitude of adults with ADHD was found to be lower than healthy group. In conclusions, Neuroimaging and psychophysiology outcome were effectively identified in adult with ADHD. Further study of neuroendocrinological factors might be related.

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How to Cite
Hung, N. C., Lin, S.-H., Chi, M. H., Chen, P. S., Lee, I. H., Chen, K. C., & Yang, Y. K. (2014). Preliminary study of neuroimaging and psychophysiology in adults with ADHD. International Journal of Child Development and Mental Health, 2(2), 23–35. Retrieved from
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