Preliminary study of neuroimaging and psychophysiology in adults with ADHD

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Published: Jul 30, 2014
Keywords:
ADHD Dopamine Iowa gambling test neuroimaging P300 amplitude

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Ni Chun Hung
Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Psychiatry, Chi-Mei Foundation Medical Center, Tainan, Taiwan
Shin-Hsien Lin
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan.
Mei Hung Chi
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Po See Chen
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, NationalCheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan
I Hui Lee
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan
Kao Chin Chen
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan. Department of Psychiatry, National Cheng Kung University, Dou-Liou Branch, Yunlin, Taiwan.
Yen Kuang Yang
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan

Abstract

Attention Deficit Hyperactivity Disorder  (ADHD) affects in both children and adults leading
to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and psychophysiology outcomes in the adults with ADHD. Participants in this study consisted of three groups: unaffected fathers of offspring with ADHD, adults with ADHD, and matched controls, were enrolled. A psychological battery was used in order to assess the participants’ cool cognitive function. Levels of dopaminergic activity were assessed by using the single positron emission computed tomography (SPECT) with [99mTc] TRODAT-1. In a pilot test for further study, the Iowa gambling
test in a mock functional MRI was conducted. Molecular neuroimaging indicated the pivotal
role of dopaminergicactivity altered a swellas functional brain imaging demonstrated difference between cool and hot executive functions. Using the Event-Related Potentials (ERP), the P300 amplitude of adults with ADHD was found to be lower than healthy group. In conclusions, Neuroimaging and psychophysiology outcome were effectively identified in adult with ADHD. Further study of neuroendocrinological factors might be related.

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How to Cite
Hung, N. C., Lin, S.-H., Chi, M. H., Chen, P. S., Lee, I. H., Chen, K. C., & Yang, Y. K. (2014). Preliminary study of neuroimaging and psychophysiology in adults with ADHD. International Journal of Child Development and Mental Health, 2(2), 23–35. Retrieved from https://he01.tci-thaijo.org/index.php/cdmh/article/view/66599
Issue
Vol. 2 No. 2 (2014): February - July 2014
Section
Original Articles


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